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HIP1 Matched Antibody Pair (542) (APMAB-542LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-HIP1 monoclonal antibody, 100 ug
Detection Antibody
Anti-HIP1 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The product of this gene is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein binds to the huntingtin protein in the brain; this interaction is lost in Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Alternative Names
Huntingtin Interacting Protein 1; Huntingtin-Interacting Protein I; HIP-I; Huntingtin-Interacting Protein 1; SHONgamma; SHONbeta; ILWEQ; HIP-1; SHON;
Entrez Gene ID
3092
UniProt ID
O00291
More Infomation

Prasad, P., Chongtham, J., Tripathi, S. C., Ganguly, N. K., Mittal, S. A., & Srivastava, T. (2023). Huntingtin Interacting Protein-1 expression is regulated via HIF2 axis in Lung Adenocarcinoma. bioRxiv, 2023-03.

Lacombe, L., Hovington, H., Brisson, H., Mehdi, S., Beillevaire, D., Émond, J. P., ... & Lévesque, E. (2023). UGT2B28 accelerates prostate cancer progression through stabilization of the endocytic adaptor protein HIP1 regulating AR and EGFR pathways. Cancer Letters, 553, 215994.

Surbhi, Goel, A., Chaturvedi, V., Verma, S., Rawat, S., Ganguly, N. K., & Mittal, S. A. (2022). Huntingtin Interacting Protein 1 (HIP1) autoantibodies as a novel potential surrogate marker for Rheumatoid Arthritis: Pilot Study. medRxiv, 2022-09.

Tamta, S., Goel, A., Chaturvedi, V., Verma, S., Rawat, S., Ganguly, N. K., & Mittal, S. A. (2022). Huntingtin Interacting Protein 1 (HIP1) autoantibodies as a novel potential surrogate marker for Rheumatoid Arthritis: Pilot Study.

Kang, J., Deng, Q. M., Peng, K. C., Li, P., Zhu, B. T., Wang, P., ... & Yang, J. J. (2022). Clinicopathological features and resistance mechanisms in HIP1‐ALK‐rearranged lung cancer: A multicenter study. Genes, Chromosomes and Cancer, 61(4), 177-186.

Murakami, T., Matsuura, R., Chutiwitoonchai, N., Takei, M., & Aida, Y. (2021). Huntingtin-Interacting Protein 1 Promotes Vpr-Induced G2 Arrest and HIV-1 Infection in Macrophages. Viruses, 13(11), 2308.

Sun, Y., Zhou, Y., Xia, J., Wen, M., Wang, X., Zhang, J., ... & Jiang, T. (2021). Abnormally high HIP1 expression is associated with metastatic behaviors and poor prognosis in ESCC. Oncology Letters, 21(2), 1-1.

Laragione, T., Brenner, M., Lahiri, A., Gao, E., Harris, C., & Gulko, P. S. (2018). Huntingtin-interacting protein 1 (HIP1) regulates arthritis severity and synovial fibroblast invasiveness by altering PDGFR and Rac1 signalling. Annals of the rheumatic diseases, 77(11), 1627-1635.

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For research use only. Not intended for any clinical use.

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