Human C1QA ELISA Kit (V2LY-0626-LY4423)

See all C1QA antibodies
Go to compare Compare Online Inquiry
Tested Data
Datasheet
SDS
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
2.45 ng/mL
Detection Range
5-1000 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
26.0 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
C1QA
Function
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Biological Process
Aging Source: ARUK-UCL
Astrocyte activation Source: ARUK-UCL
Cell-cell signaling Source: ProtInc
Complement activation Source: Reactome
Complement activation, classical pathway Source: Reactome
Complement-mediated synapse pruning Source: ARUK-UCL
Innate immune response Source: UniProtKB-KW
Microglial cell activation Source: ARUK-UCL
Neuron remodeling Source: ARUK-UCL
Positive regulation of neuron death Source: ARUK-UCL
Regulation of complement activation Source: Reactome
Response to iron ion Source: Ensembl
Synapse organization Source: ARUK-UCL
Synapse pruning Source: ARUK-UCL
Vertebrate eye-specific patterning Source: ARUK-UCL
Viral process Source: UniProtKB-KW
Cellular Location
Secreted
Involvement in disease
Complement component C1q deficiency (C1QD): A disorder caused by impaired activation of the complement classical pathway. It generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis.
PTM
O-linked glycans are assumed to be the Glc-Gal disaccharides typically found as secondary modifications of hydroxylated lysines in collagen-like domains.

Chen, L. H., Liu, J. F., Lu, Y., He, X. Y., Zhang, C., & Zhou, H. H. (2021). Complement C1q (C1qA, C1qB, and C1qC) May Be a Potential Prognostic Factor and an Index of Tumor Microenvironment Remodeling in Osteosarcoma. Frontiers in oncology, 11, 1643.

Mamoor, S. (2021). Chain A, B, and C of the complement component C1q are differentially expressed in human epithelial ovarian cancer.

Brym, P., Zabolewicz, T., & Kaminski, S. (2018). Differential expression of complement subcomponent C1qA in blood samples of healthy and BLV-infected Polish Holstein-Friesian cows. Anim Sci Pap Rep, 36, 45-55.

Fonseca, M. I., Chu, S. H., Hernandez, M. X., Fang, M. J., Modarresi, L., Selvan, P., ... & Tenner, A. J. (2017). Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain. Journal of neuroinflammation, 14(1), 1-15.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Human C1QA ELISA Kit?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse C1qa ELISA Kit (CAT#: V2LY-0626-LY2212)

Pig C1QA ELISA Kit (CAT#: V2LY-0626-LY955)

C1QA Matched Antibody Pair (154) (CAT#: APMAB-154LY)

Antibody Pairs

C1QA Matched Antibody Pair (154) (CAT#: APMAB-154LY)

Related Products

C1QA Matched Antibody Pair (154) (CAT#: APMAB-154LY)

Rat Anti-C1QA Recombinant Antibody (CBXC-1703) (CAT#: CBMAB-C5928-CQ)

Mouse Anti-C1QA Recombinant Antibody (CBXC-2526) (CAT#: CBMAB-C5950-CQ)

Mouse Anti-C1QA Recombinant Antibody (CBHb031) (CAT#: CBMAB-Hb080-LY)

Rat Anti-C1QA Recombinant Antibody (7H8) (CAT#: CBMAB-1234-CN)

Mouse Anti-C1QA Recombinant Antibody (CBCNC-126) (CAT#: CBMAB-C1117-CN)

Mouse C1qa ELISA Kit (CAT#: V2LY-0626-LY2212)

Pig C1QA ELISA Kit (CAT#: V2LY-0626-LY955)

Mouse Anti-C1QA Recombinant Antibody (CBT4829) (CAT#: V2LY-0625-LY596)

Rabbit Anti-C1QA Recombinant Antibody (HL1695) (CAT#: CBMAB-C7646-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry
Request bulk or custom quote Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.