Human CCL17 ELISA Kit (V2LY-0626-LY501)

Name: Human CCL17 ELISA Kit
SKU: V2LY-0626-LY501
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.0055 ng/mL

Detection Range

0.01-4 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Human

Assay Type

Sandwich

Reactivity

Human

Assay Time

1.5 h

Molecule Mass

10.5 kDa

Components

Pre-coated ELISA Plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

chemokine (C-C motif) ligand 17

Function

Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.

Biological Process

Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell-cell signaling Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Multicellular organism development Source: ProtInc
Negative regulation of myoblast differentiation Source: Ensembl
Neutrophil chemotaxis Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central

Cellular Location

Secreted

Tang, N., Zhang, Y. Y., Cheng, J. H., Zhao, Z. B., & Fan, Y. (2021). Cross-talk between CXC chemokine ligand 10-CXC chemokine receptor 3 axis and CC chemokine ligand 17-CC chemokine receptor 4 axis in the pathogenesis of oral lichen planus. Hua xi kou Qiang yi xue za zhi= Huaxi Kouqiang Yixue Zazhi= West China Journal of Stomatology, 39(4), 405-412.

Feng, S., Wang, L., Wang, Y., Wang, Y., Chen, Y., Tian, R., ... & Zhang, S. (2021). Association between serum chemokine CC-motif ligand 17 and prognosis of patients at risk for coronary heart disease.

Dong, Y., Gao, S., Zhang, X., Kou, J., Liu, J., Ye, T., & Shen, H. (2021). CCL17 and CCL22 induce CCR4 receptor expression and promote cytokine-induced killer cells migration. Anti-cancer Drugs.

Chen, Y. T., Hsu, H., Lin, C. C., Pan, S. Y., Liu, S. Y., Wu, C. F., ... & Lin, S. L. (2020). Inflammatory macrophages switch to CCL17‐expressing phenotype and promote peritoneal fibrosis. The Journal of pathology, 250(1), 55-66.

Wilkinson, H. N., Roberts, E. R., Stafford, A. R., Banyard, K. L., Matteucci, P., Mace, K. A., & Hardman, M. J. (2019). Tissue iron promotes wound repair via m2 macrophage polarization and the chemokine (cc motif) ligands 17 and 22. The American journal of pathology, 189(11), 2196-2208.

Li, J., Yang, C., Yang, J., & Zou, L. (2019). Down-regulation of CCL17 in cancer-associated fibroblasts inhibits cell migration and invasion of breast cancer through ERK1/2 pathway. Cancer management and research, 11, 7439.

Lee, M. C., Saleh, R., Achuthan, A., Fleetwood, A. J., Förster, I., Hamilton, J. A., & Cook, A. D. (2018). CCL17 blockade as a therapy for osteoarthritis pain and disease. Arthritis research & therapy, 20(1), 1-10.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant CCL17 protein (CAT#: V2LY-0526-LY7058)

Human Recombinant CCL17 protein, His Tag (CAT#: V2LY-0526-LY7059)

Mouse Recombinant CCL17 protein (CAT#: V2LY-0526-LY8948)

Rhesus Recombinant CCL17 protein, His Tag (CAT#: V2LY-0526-LY9793)

Related Products

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Mouse Anti-CCL17 Recombinant Antibody (5C8C9) (CAT#: CBMAB-C7433-LY)

Mouse Recombinant CCL17 protein (CAT#: V2LY-0526-LY8948)

Mouse Anti-CCL17 Recombinant Antibody (1F11) (CAT#: CBMAB-C4014-LY)

Rat Anti-CCL17 Recombinant Antibody (9K49) (CAT#: CBMAB-C9804-LY)

Mouse Anti-CCL17 Recombinant Antibody (CBFYC-0940) (CAT#: CBMAB-C0996-FY)

Mouse Anti-CCL17 Recombinant Antibody (2E7) (CAT#: CBMAB-A1174-LY)

Human Recombinant CCL17 protein, His Tag (CAT#: V2LY-0526-LY7059)

Human Recombinant CCL17 protein (CAT#: V2LY-0526-LY7058)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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