CCL17

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq]
Full Name
chemokine (C-C motif) ligand 17
Function
Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell-cell signaling Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Multicellular organism development Source: ProtInc
Negative regulation of myoblast differentiation Source: Ensembl
Neutrophil chemotaxis Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central
Cellular Location
Secreted
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Anti-CCL17 antibodies

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Mouse Anti-CCL17 Recombinant Antibody (CBFYC-0943) (CBMAB-C0999-FY)

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Target: CCL17
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-0943
Application*: WB, E, F
Datasheet SDS

Rat Anti-CCL17 Recombinant Antibody (110946) (CBMAB-C0198-LY)

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Target: CCL17
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 110946
Application*: WB
Datasheet SDS

Mouse Anti-CCL17 Recombinant Antibody (2E7) (CBMAB-A1174-LY)

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Target: CCL17
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2E7
Application*: WB, E
Datasheet SDS

Rat Anti-CCL17 Recombinant Antibody (9K49) (CBMAB-C9804-LY)

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Target: CCL17
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 9K49
Application*: WB, N
Functional Assay
Datasheet SDS

Mouse Anti-CCL17 Recombinant Antibody (CBFYC-0944) (CBMAB-C1000-FY)

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Target: CCL17
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0944
Application*: E
Datasheet SDS

Mouse Anti-CCL17 Recombinant Antibody (CBFYC-0940) (CBMAB-C0996-FY)

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Target: CCL17
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0940
Application*: E
Datasheet SDS

Mouse Anti-CCL17 Recombinant Antibody (6J30) (CBMAB-C8367-LY)

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Target: CCL17
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6J30
Application*: WB
Datasheet SDS

Mouse Anti-CCL17 Recombinant Antibody (5C8C9) (CBMAB-C7433-LY)

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Target: CCL17
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5C8C9
Application*: E
Datasheet SDS

Mouse Anti-CCL17 Recombinant Antibody (1F11) (CBMAB-C4014-LY)

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Target: CCL17
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1F11
Application*: E, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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