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CCL17

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq]

Full Name

chemokine (C-C motif) ligand 17

Function

Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.

Biological Process

Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell-cell signaling Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Multicellular organism development Source: ProtInc
Negative regulation of myoblast differentiation Source: Ensembl
Neutrophil chemotaxis Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central

Cellular Location

Secreted

Anti-CCL17 antibodies

Rat Anti-CCL17 Recombinant Antibody (110946) (CBMAB-C0198-LY)

SDS

Target: CCL17

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: 110946

Application*: WB

Rat Anti-CCL17 Recombinant Antibody (110904) (CBMAB-C0197-LY)

SDS

Target: CCL17

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: 110904

Application*: N, EC

Mouse Anti-CCL17 Recombinant Antibody (CBXC-1243) (CBMAB-C5572-CQ)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-1243

Application*: IS

Rat Anti-CCL17 Recombinant Antibody (CBXC-2649) (CBMAB-C3505-CQ)

SDS

Target: CCL17

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBXC-2649

Application*: WB, N

Mouse Anti-CCL17 Recombinant Antibody (CBXC-1244) (CBMAB-C1511-CQ)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-1244

Application*: N, EC

Mouse Anti-CCL17 Recombinant Antibody (CBFYC-0944) (CBMAB-C1000-FY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYC-0944

Application*: F

Mouse Anti-CCL17 (AA 24-94) Recombinant Antibody (CBFYC-0943) (CBMAB-C0999-FY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBFYC-0943

Application*: E, IF

Rat Anti-CCL17 Recombinant Antibody (CBFYC-0941) (CBMAB-C0997-FY)

SDS

Target: CCL17

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBFYC-0941

Application*: N, EC

Mouse Anti-CCL17 Recombinant Antibody (CBFYC-0940) (CBMAB-C0996-FY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-0940

Application*: WB

Rat Anti-CCL17 Recombinant Antibody (CBFYC-0939) (CBMAB-C0995-FY)

SDS

Target: CCL17

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBFYC-0939

Application*: N, WB

Rabbit Anti-CCL17 Recombinant Antibody (CBYJT-1061) (CBMAB-T0071-YJ)

SDS

Target: CCL17

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: CBYJT-1061

Application*: P, WB

Mouse Anti-CCL17 Recombinant Antibody (CBYJT-1060) (CBMAB-T0070-YJ)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-1060

Application*: WB

Mouse Anti-CCL17 Recombinant Antibody (2E7) (CBMAB-A1174-LY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 2E7

Application*: WB, E

Rat Anti-CCL17 Recombinant Antibody (9K49) (CBMAB-C9804-LY)

SDS

Target: CCL17

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: 9K49

Application*: WB, N

Mouse Anti-CCL17 Recombinant Antibody (MM0141-6J30) (CBMAB-C9805-LY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: MM0141-6J30

Application*: WB

Mouse Anti-CCL17 Recombinant Antibody (T48-854) (CBMAB-C9802-LY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: T48-854

Application*: F

Mouse Anti-CCL17 Recombinant Antibody (14L92) (CBMAB-C1404-CN)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 14L92

Application*: WB

Mouse Anti-CCL17 Recombinant Antibody (CBYY-C1064) (CBMAB-C2501-YY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-C1064

Application*: WB

Mouse Anti-CCL17 Recombinant Antibody (CBYY-C1063) (CBMAB-C2500-YY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-C1063

Application*: N, E(Cap)

Mouse Anti-CCL17 Recombinant Antibody (6J30) (CBMAB-C8367-LY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 6J30

Application*: WB

Mouse Anti-CCL17 Recombinant Antibody (5C8C9) (CBMAB-C7433-LY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 5C8C9

Application*: E, WB

Mouse Anti-CCL17 Recombinant Antibody (1F11) (CBMAB-C4014-LY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 1F11

Application*: E, IF

Mouse Anti-CCL17 Recombinant Antibody (54026) (CBMAB-C3419-LY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 54026

Application*: N, EC

Mouse Anti-CCL17 Recombinant Antibody (54015) (CBMAB-C3411-LY)

SDS

Target: CCL17

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 54015

Application*: WB, IS, MC

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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