Human CNTN5 ELISA Kit (V2LY-0626-LY4440)

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Tested Data
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0073 ng/mL
Detection Range
0.015-3 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
120.7 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Contactin 5
Function
Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity).
Biological Process
Cell adhesion Source: UniProtKB-KW
Presynapse assembly Source: Ensembl
Sensory perception of sound Source: Ensembl
Cellular Location
Cell membrane

Schmilovich, Z., Huguet, G., He, Q., Musa-Johnson, A., Douard, E., Loum, M. A., ... & Rouleau, G. A. (2021). Copy-Number Variants in The Contactin-5 Gene Are a Potential Risk Factor for Autism Spectrum Disorder.

Dauar, M. T., Picard, C., Rosa‐Neto, P., Villeneuve, S., Poirier, J., & Prevent‐AD Research Group. (2021). CNTN5 is associated with disease risk and pathology throughout the Alzheimer’s disease continuum. Alzheimer's & Dementia, 17, e052359.

Kleijer, K. T., van Nieuwenhuize, D., Spierenburg, H. A., Gregorio-Jordan, S., Kas, M. J., & Burbach, J. P. H. (2018). Structural abnormalities in the primary somatosensory cortex and a normal behavioral profile in Contactin-5 deficient mice. Cell Adhesion & Migration, 12(1), 5-18.

Smirnov, A. V., Kontsevaya, G. V., Feofanova, N. A., Anisimova, M. V., Serova, I. A., Gerlinskaya, L. A., ... & Serov, O. L. (2018). Unexpected phenotypic effects of a transgene integration causing a knockout of the endogenous Contactin-5 gene in mice. Transgenic research, 27(1), 1-13.

Peng, Y. R., Tran, N. M., Krishnaswamy, A., Kostadinov, D., Martersteck, E. M., & Sanes, J. R. (2017). Satb1 regulates contactin 5 to pattern dendrites of a mammalian retinal ganglion cell. Neuron, 95(4), 869-883.

Oguro-Ando, A., Zuko, A., Kleijer, K. T., & Burbach, J. P. H. (2017). A current view on contactin-4,-5, and-6: Implications in neurodevelopmental disorders. Molecular and Cellular Neuroscience, 81, 72-83.

Smirnov, A. V., Feofanova, N. A., Kontsevaya, G. V., Anisimova, M. V., Kovrigin, I. I., Serova, I. A., ... & Battulin, N. R. (2017). Morphophysiological effects of insertional mutagenesis of the contactin 5 (Cntn5) gene in transgenic mice. Russian Journal of Genetics: Applied Research, 7(8), 799-805.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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