Human FCGR3B ELISA Kit (V2LY-0626-LY4828)

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Tested Data
Datasheet
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Basic Information

Sensitivity
0.29 ng/mL
Detection Range
0.5-200 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
26.2 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Fc Fragment Of IgG Receptor IIIb
Research Area
Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Biological Process
Cell surface receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Regulation of immune response Source: GO_Central
Cellular Location
Cell membrane; Secreted. Secreted after cleavage.
PTM
Glycosylated. Glycosylation plays an inhibitory role in the interaction with IgG3.
The soluble form is produced by a proteolytic cleavage.

Alyasova, A. V., Amoev, Z. V., Shkola, O. O., Novikov, D. V., Selivanova, S. G., & Novikov, V. V. (2022). Messenger RNA of FCGR3A and FCGR3B Genes as Monitoring Markers of Clear Cell Renal Adenocarcinoma (a Pilot Study). Современные технологии в медицине, 14(3 (eng)), 22-26.

Ines, M., Moalla, M., Aicha, B. T., Selma, B., Leila, R., Rawdha, T., ... & Imen, S. (2022). Impact of FCGR2A R131h, FCGR3A F158V and FCGR3B NA1/NA2 Polymorphisms on Response to Fc-Containing TNF Inhibitor in Rheumatoid Arthritis. FCGR3A F158V and FCGR3B NA1/NA2 Polymorphisms on Response to Fc-Containing TNF Inhibitor in Rheumatoid Arthritis (3/28/2022).

Nassir, N., Tambi, R., Bankapur, A., Al Heialy, S., Karuvantevida, N., Khansaheb, H. H., ... & Uddin, M. (2021). Single-cell transcriptome identifies FCGR3B upregulated subtype of alveolar macrophages in patients with critical COVID-19. Iscience, 24(9), 103030.

Alberici, F., Bonatti, F., Adorni, A., Daminelli, G., Sinico, R. A., Gregorini, G., ... & Vaglio, A. (2020). FCGR3B polymorphism predicts relapse risk in eosinophilic granulomatosis with polyangiitis. Rheumatology, 59(11), 3563-3566.

Dwomoh, D., Adu, B., Dodoo, D., Theisen, M., Iddi, S., & Gerds, T. A. (2020). Evaluating the predictive performance of malaria antibodies and FCGR3B gene polymorphisms on Plasmodium falciparum infection outcome: a prospective cohort study. Malaria Journal, 19(1), 1-12.

Kilani, B., Cornélis, F., Olaso, R., Chaudru, V., & Petit-Teixeira, E. (2019). Investigation of candidate gene copy number identifies FCGR3B as a potential biomarker for rheumatoid arthritis. Clinical and experimental rheumatology, 37(6), 923-928.

Dahmani, C. A., Benzaoui, A., Amroun, H., Zemani‐Fodil, F., Petit‐Teixeira, E., & Boudjema, A. (2019). Association study of copy number variants in CCL3L1, FCGR3A and FCGR3B genes with risk of ankylosing spondylitis in a West Algerian population. International Journal of Immunogenetics, 46(6), 437-443.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant FCGR3B (NA1 allotype) protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY2692)

Human Recombinant FCGR3B (NA1 allotype) protein, His Tag (CAT#: V2LY-0526-LY2693)

Human Recombinant FCGR3B (NA2 allotype) protein, His & AVI Tag (CAT#: V2LY-0526-LY2694)

Human Recombinant FCGR3B (NA2 allotype) protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY2695)

Human Recombinant FCGR3B (NA2 allotype) protein, His Tag (CAT#: V2LY-0526-LY2696)

Human Recombinant FCGR3B (NA2 allotype) protein, His Tag-1 (CAT#: V2LY-0526-LY2697)

Human Recombinant FCGR3B (SH allotype) protein, His Tag (CAT#: V2LY-0526-LY2698)

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Human Recombinant FCGR3B (NA2 allotype) protein, His Tag-1 (CAT#: V2LY-0526-LY2697)

Mouse Anti-FCGR3B Recombinant Antibody (CBYY-C2492) (CAT#: V2LY-0925-LY1028)

Human Recombinant FCGR3B (NA2 allotype) protein, His Tag (CAT#: V2LY-0526-LY2696)

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Human Recombinant FCGR3B (NA1 allotype) protein, His Tag (CAT#: V2LY-0526-LY2693)

Human Recombinant FCGR3B (NA1 allotype) protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY2692)

Mouse Anti-FCGR3B Recombinant Antibody (CBXF-2590) (CAT#: V2LY-0925-LY1023)

Isotype control

For research use only. Not intended for any clinical use.

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