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FCGR3B

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]
Full Name
Fc Fragment Of IgG Receptor IIIb
Research Area
Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Biological Process
Cell surface receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Regulation of immune response Source: GO_Central
Cellular Location
Cell membrane; Secreted. Secreted after cleavage.
PTM
Glycosylated. Glycosylation plays an inhibitory role in the interaction with IgG3.
The soluble form is produced by a proteolytic cleavage.

Anti-FCGR3B antibodies

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Mouse Anti-FCGR3B Recombinant Antibody (CB231A) (CBMAB-CA231LY)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CB231A
Application*: ELISA, WB

Mouse Anti-FCGR3B Recombinant Antibody (CB213) (CBMAB-CS213LY)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB213
Application*: IF, FC

Mouse Anti-FCGR3B Recombinant Antibody (CB212) (CBMAB-CS212LY)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB212
Application*: IF, FC

Mouse Anti-FCGR3B Recombinant Antibody (CB211) (CBMAB-CS211LY)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB211
Application*: IF, FC

Mouse Anti-FCGR3B Recombinant Antibody (CB210) (CBMAB-CS210LY)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB210
Application*: IF, FC

Mouse Anti-FCGR3B Recombinant Antibody (CB209) (CBMAB-CS209LY)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB209
Application*: IF, FC

Mouse Anti-FCGR3B Recombinant Antibody (MM0272-5L11) (CBMAB-C11597-LY)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: MM0272-5L11
Application*: WB, F

Mouse Anti-FCGR3B Recombinant Antibody (1D3) (CBMAB-C3495-CN)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: 1D3
Application*: FC

Mouse Anti-FCGR3B Recombinant Antibody (5L11) (CBMAB-C7828-LY)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 5L11
Application*: C, WB

Human Anti-FCGR3B Recombinant Antibody (CBXC-0887) (CBMAB-C2002-CQ)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0887
Application*: F

Mouse Anti-FCGR3B Recombinant Antibody (CBYY-C2492) (CBMAB-C3932-YY)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYY-C2492
Application*: F, WB

Mouse Anti-FCGR3B Recombinant Antibody (CBFYC-2697) (CBMAB-C2771-FY)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-2697
Application*: P

Mouse Anti-FCGR3B Recombinant Antibody (CBFYC-2696) (CBMAB-C2770-FY)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-2696
Application*: E

Mouse Anti-FCGR3B Recombinant Antibody (CBXF-3575) (CBMAB-F2081-CQ)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBXF-3575
Application*: F

Mouse Anti-FCGR3B Recombinant Antibody (CBXF-2590) (CBMAB-F0134-CQ)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-2590
Application*: F

Mouse Anti-FCGR3B Recombinant Antibody (CBXF-2589) (CBMAB-F0133-CQ)

Datasheet Datasheet SDS SDS
Target: FCGR3B
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2589
Application*: F
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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