Human GABARAPL2 ELISA Kit (V2LY-0626-LY4605)
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Basic Information
- Pre-coated ELISA plate: 12 wells * 8 detachable strips
- Standard solution: 0.5ml x1
- Standard diluent: 3ml x1
- Streptavidin-HRP: 6ml x1
- Stop solution: 6ml x1
- Substrate solution A: 6ml x1
- Substrate solution B: 6ml x1
- Wash buffer concentrate (25x): 20ml x1
- Biotinylated antibody: 1ml x1
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation (By similarity).
It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity).
Involved in autophagy (PubMed:20418806, PubMed:23209295).
Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (PubMed:20418806, PubMed:23209295).
Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20418806, PubMed:23209295).
Autophagy Source: UniProtKB
Autophagy of mitochondrion Source: GO_Central
Cellular response to nitrogen starvation Source: GO_Central
Intra-Golgi vesicle-mediated transport Source: UniProtKB
Macroautophagy Source: GO_Central
Negative regulation of proteasomal protein catabolic process Source: BHF-UCL
Positive regulation of ATPase activity Source: UniProtKB
Protein localization to endoplasmic reticulum Source: UniProtKB
Protein transport Source: UniProtKB-KW
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Human Recombinant GABARAPL2 protein, His Tag (CAT#: V2LY-0526-LY4234)
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Human Recombinant GABARAPL2 protein, His Tag (CAT#: V2LY-0526-LY4234)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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