Human IL1RL1 ELISA Kit (V2LY-0626-LY4708)

Name: Human IL1RL1 ELISA Kit
SKU: V2LY-0626-LY4708
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.014 ng/mL

Detection Range

0.03-9 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Human

Assay Type

Sandwich

Reactivity

Human

Assay Time

1.5 h

Molecule Mass

63.4 kDa

Components

Pre-coated ELISA Plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

Interleukin 1 Receptor Like 1

Function

Receptor for interleukin-33 (IL-33); signaling requires association of the coreceptor IL1RAP. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function.

Isoform B
Inhibits IL-33 signaling.

Cellular Location

Isoform C: Cell membrane
Isoform B: Secreted; Cell membrane

Topology

Extracellular: 19-328
Helical: 329-349
Cytoplasmic: 350-556

Jiang, Y., Zhou, X., Wong, H. Y., Ouyang, L., Ip, F. C., Chau, V. M., ... & Ip, N. Y. (2022). An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease. Nature aging, 2(7), 616-634.

Li, Z., Ren, J., Zhang, J., Wang, X., Liu, Y., & Wang, Q. (2022). Association between IL1RL1 gene polymorphisms and allergic rhinitis risk in the Chinese Han population. Journal of Clinical Laboratory Analysis, 36(11), e24747.

Yu, G. I., Song, D. K., & Shin, D. H. (2020). Associations of IL1RAP and IL1RL1 gene polymorphisms with obesity and inflammation mediators. Inflammation Research, 69, 191-202.

Fulgione, A., Papaianni, M., Cuomo, P., Paris, D., Romano, M., Tuccillo, C., ... & Capparelli, R. (2020). Interaction between MyD88, TIRAP and IL1RL1 against Helicobacter pylori infection. Scientific reports, 10(1), 15831.

Dijk, F. N., Vijverberg, S. J., Hernandez‐Pacheco, N., Repnik, K., Karimi, L., Mitratza, M., ... & Koppelman, G. H. (2020). IL1RL1 gene variations are associated with asthma exacerbations in children and adolescents using inhaled corticosteroids. Allergy, 75(4), 984.

Wang, Y., Luo, H., Wei, M., Becker, M., Hyde, R. K., & Gong, Q. (2020). IL-33/IL1RL1 axis regulates cell survival through the p38 MAPK pathway in acute myeloid leukemia. Leukemia Research, 96, 106409.

Portelli, M. A., Dijk, F. N., Ketelaar, M. E., Shrine, N., Hankinson, J., Bhaker, S., ... & Sayers, I. (2020). Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium. JCI insight, 5(8).

Ahmadi, M., Fathi, F., Fouladi, S., Alsahebfosul, F., Manian, M., & Eskandari, N. (2019). Serum IL-33 level and IL-33, IL1RL1 gene polymorphisms in asthma and multiple sclerosis patients. Current Molecular Medicine, 19(5), 357-363.

Schaunaman, N., Sanchez, A., Dimasuay, K. G., Pavelka, N., Numata, M., Alam, R., ... & Chu, H. W. (2019). Interleukin 1 receptor-like 1 (IL1RL1) promotes airway bacterial and viral infection and inflammation. Infection and immunity, 87(7), 10-1128.

Dijk, F. N., Xu, C., Melén, E., Carsin, A. E., Kumar, A., Nolte, I. M., ... & Koppelman, G. H. (2018). Genetic regulation of IL1RL1 methylation and IL1RL1-a protein levels in asthma. European Respiratory Journal, 51(3).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus Recombinant IL1RL1 protein, His Tag (CAT#: V2LY-0526-LY1646)

Cynomolgus Recombinant IL1RL1 protein, His Tag-1 (CAT#: V2LY-0526-LY1647)

Human Recombinant IL1RL1 protein (CAT#: V2LY-0526-LY6952)

Human Recombinant IL1RL1 protein-1 (CAT#: V2LY-0526-LY6954)

Human Recombinant IL1RL1 protein, hFc Tag (CAT#: V2LY-0526-LY6955)

Human Recombinant IL1RL1 protein, His Tag (CAT#: V2LY-0526-LY6956)

Human Recombinant IL1RL1 (isoform a) protein, His Tag (CAT#: V2LY-0526-LY6957)

Mouse Recombinant IL1RL1 protein, hFc Tag (CAT#: V2LY-0526-LY8938)

Mouse Recombinant IL1RL1 protein, His Tag (CAT#: V2LY-0526-LY8939)

Mouse Il1rl1 ELISA Kit (CAT#: V2LY-0626-LY5820)

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Mouse Recombinant IL1RL1 protein, hFc Tag (CAT#: V2LY-0526-LY8938)

Human Recombinant IL1RL1 (isoform a) protein, His Tag (CAT#: V2LY-0526-LY6957)

Human Recombinant IL1RL1 protein (CAT#: V2LY-0526-LY6952)

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Isotype control

For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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