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IL1RL1

The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.
Full Name
Interleukin 1 Receptor Like 1
Function
Receptor for interleukin-33 (IL-33); signaling requires association of the coreceptor IL1RAP. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function.

Isoform B
Inhibits IL-33 signaling.
Cellular Location
Isoform C: Cell membrane
Isoform B: Secreted; Cell membrane
Topology
Extracellular: 19-328
Helical: 329-349
Cytoplasmic: 350-556

Anti-IL1RL1 antibodies

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Mouse Anti-IL1RL1 Recombinant Antibody (S7B7) (CBMAB-S6536-CQ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: S7B7
Application*: E

Mouse Anti-IL1RL1 Recombinant Antibody (HB12) (CBMAB-S6355-CQ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HB12
Application*: F, IH, IP, WB

Mouse Anti-IL1RL1 Recombinant Antibody (FB9) (CBMAB-S6326-CQ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: FB9
Application*: E, F, IP, WB

Mouse Anti-IL1RL1 Recombinant Antibody (CBXS-2594) (CBMAB-S5350-CQ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-2594
Application*: N, WB

Mouse Anti-IL1RL1 Recombinant Antibody (CBXS-1994) (CBMAB-S4762-CQ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-1994
Application*: WB, N, EC

Rat Anti-IL1RL1 Recombinant Antibody (CBXS-1727) (CBMAB-S4558-CQ)

Datasheet SDS
Target: IL1RL1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXS-1727
Application*: WB

Rabbit Anti-IL1RL1 Recombinant Antibody (CBXS-1705) (CBMAB-S4543-CQ)

Datasheet SDS
Target: IL1RL1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1705
Application*: WB

Mouse Anti-IL1RL1 Recombinant Antibody (B-L42) (CBMAB-S2988-CQ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: B-L42
Application*: F, WB

Mouse Anti-IL1RL1 Recombinant Antibody (B-D52) (CBMAB-S2982-CQ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: B-D52
Application*: E

Mouse Anti-IL1RL1 Recombinant Antibody (B-A52) (CBMAB-S2979-CQ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-A52
Application*: E

Mouse Anti-IL1RL1 Recombinant Antibody (CBXS-5551) (CBMAB-S2758-CQ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-5551
Application*: E, WB

Mouse Anti-IL1RL1 Recombinant Antibody (CBXS-5206) (CBMAB-S2423-CQ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBXS-5206
Application*: WB, N

Mouse Anti-IL1RL1 Recombinant Antibody (CBXS-4352) (CBMAB-S1596-CQ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4352
Application*: F, IP, WB

Mouse Anti-IL1RL1 Recombinant Antibody (B4E6) (CBMAB-S0302-CQ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B4E6
Application*: F, IH

Rat Anti-IL1RL1 Recombinant Antibody (CBXS-1726) (CBMAB-S0103-CQ)

Datasheet SDS
Target: IL1RL1
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBXS-1726
Application*: F

Rat Anti-Il1rl1 Recombinant Antibody (CBYJT-1391) (CBMAB-T0413-YJ)

Datasheet SDS
Target: IL1RL1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYJT-1391
Application*: F, IP

Mouse Anti-IL1RL1 Recombinant Antibody (CBYJT-1389) (CBMAB-T0411-YJ)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Chicken
Clone: CBYJT-1389
Application*: F, IP

Mouse Anti-IL1RL1 Recombinant Antibody (CBYY-I1833) (CBMAB-I3003-YY)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1833
Application*: F

Rat Anti-IL1RL1 Recombinant Antibody (CBYY-I1700) (CBMAB-I2870-YY)

Datasheet SDS
Target: IL1RL1
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Mouse
Clone: CBYY-I1700
Application*: F, BL

Mouse Anti-IL1RL1 Recombinant Antibody (CBYY-I1230) (CBMAB-I2399-YY)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Pig, Rat
Clone: CBYY-I1230
Application*: E, WB, IH

Mouse Anti-IL1RL1 Recombinant Antibody (ST33868) (CBMAB-I1103-YY)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: ST33868
Application*: E, WB

Rat Anti-IL1RL1 Recombinant Antibody (CBYY-I0453) (CBMAB-I1054-YY)

Datasheet SDS
Target: IL1RL1
Host: Rat
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: CBYY-I0453
Application*: F, FN

Rat Anti-IL1RL1 Recombinant Antibody (CBYY-I0452) (CBMAB-I1053-YY)

Datasheet SDS
Target: IL1RL1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-I0452
Application*: F

Mouse Anti-IL1RL1 Recombinant Antibody (2A5) (CBMAB-I0469-YY)

Datasheet SDS
Target: IL1RL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2A5
Application*: F, IP, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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