Human IL22 ELISA Kit (V2LY-0626-LY215)

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Tested Data
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Basic Information

Sensitivity
0.0025 ng/mL
Detection Range
0.005-1.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
20.0 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
interleukin 22
Function
Cytokine that contributes to the inflammatory response in vivo.
Biological Process
Acute-phase response1 PublicationNAS:UniProtKB
Inflammatory response1 PublicationNAS:UniProtKB
Response to glucocorticoidIEA:Ensembl
Cellular Location
Secreted

Han, H., Davidson, L. A., Fan, Y. Y., Landrock, K. K., Jayaraman, A., Safe, S. H., & Chapkin, R. S. (2022). Loss of aryl hydrocarbon receptor suppresses the response of colonic epithelial cells to IL22 signaling by upregulating SOCS3. American Journal of Physiology-Gastrointestinal and Liver Physiology, 322(1), G93-G106.

Ghimire, S., Ederer, K. U., Meedt, E., Weber, D., Matos, C., Hiergeist, A., ... & Bülow, S. (2022). Low intestinal IL22 associates with increased transplant-related mortality after allogeneic stem cell transplantation. Frontiers in immunology, 13, 857400.

Kumar, A., Patel, V. S., Harding, J. N., You, D., & Cormier, S. A. (2021). Exposure to combustion derived particulate matter exacerbates influenza infection in neonatal mice by inhibiting IL22 production. Particle and fibre toxicology, 18(1), 1-11.

Shaler, C. R., Parco, A. A., Elhenawy, W., Dourka, J., Jury, J., Verdu, E. F., & Coombes, B. K. (2021). Psychological stress impairs IL22-driven protective gut mucosal immunity against colonising pathobionts. Nature Communications, 12(1), 6664.

Zou, J., Reddivari, L., Shi, Z., Li, S., Wang, Y., Bretin, A., ... & Gewirtz, A. T. (2021). Inulin fermentable fiber ameliorates type I diabetes via IL22 and short-chain fatty acids in experimental models. Cellular and molecular gastroenterology and hepatology, 12(3), 983-1000.

Cheng, B., Rong, A., Zhou, Q., & Li, W. (2020). LncRNA LINC00662 promotes colon cancer tumor growth and metastasis by competitively binding with miR-340-5p to regulate CLDN8/IL22 co-expression and activating ERK signaling pathway. Journal of Experimental & Clinical Cancer Research, 39(1), 1-21.

Li, Z., Liang, X., Liu, W., Zhao, Y., Yang, H., Li, W., ... & Martyniuk, C. J. (2020). Elucidating mechanisms of immunotoxicity by benzotriazole ultraviolet stabilizers in zebrafish (Danio rerio): Implication of the AHR-IL17/IL22 immune pathway. Environmental Pollution, 262, 114291.

Zwarycz, B., Gracz, A. D., Rivera, K. R., Williamson, I. A., Samsa, L. A., Starmer, J., ... & Magness, S. T. (2019). IL22 inhibits epithelial stem cell expansion in an ileal organoid model. Cellular and molecular gastroenterology and hepatology, 7(1), 1-17.

Pollock, R. A., Zaman, L., Chandran, V., & Gladman, D. D. (2019). Epigenome-wide analysis of sperm cells identifies IL22 as a possible germ line risk locus for psoriatic arthritis. PLoS One, 14(2), e0212043.

Khosravi, N., Caetano, M. S., Cumpian, A. M., Unver, N., De la Garza Ramos, C., Noble, O., ... & Moghaddam, S. J. (2018). IL22 promotes kras-mutant lung cancer by induction of a protumor immune response and protection of stemness properties. Cancer immunology research, 6(7), 788-797.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-IL22 Recombinant Antibody (CAT#: CBMAB-BR305LY)

Human Recombinant IL22 protein, His Tag (CAT#: V2LY-0526-LY4840)

Human Recombinant IL22 protein (CAT#: V2LY-0526-LY4841)

Mouse Il22 ELISA Kit (CAT#: V2LY-0626-LY1435)

Related Products

Mouse Anti-IL22 Recombinant Antibody (CBYY-I0186) (CAT#: CBMAB-I0506-YY)

Mouse Anti-IL22 Recombinant Antibody (A537) (CAT#: CBMAB-AP3769LY)

Rat Anti-IL22 Recombinant Antibody (CBYY-I0796) (CAT#: CBMAB-I1773-YY)

Mouse Anti-IL22 Recombinant Antibody (CBT2459) (CAT#: V2LY-0625-LY1607)

Rat Anti-IL22 Recombinant Antibody (140301) (CAT#: CBMAB-I0501-YY)

Rat Anti-IL22 Recombinant Antibody (CBYY-I0359) (CAT#: CBMAB-I0914-YY)

Mouse Anti-IL22 Recombinant Antibody (CAT#: CBMAB-BR305LY)

Rat Anti-IL22 Recombinant Antibody (CBYY-I0187) (CAT#: CBMAB-I0507-YY)

Mouse Anti-IL22 Recombinant Antibody (CBYY-I0793) (CAT#: CBMAB-I1768-YY)

Human Recombinant IL22 protein (CAT#: V2LY-0526-LY4841)

Isotype control

For research use only. Not intended for any clinical use.

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