Human IL31 ELISA Kit (V2LY-0626-LY3720)

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Tested Data
Datasheet
SDS
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Basic Information

Sensitivity
0.0012 ng/mL
Detection Range
0.002-0.6 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
18.2 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Interleukin 31
Function
Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR (PubMed:15184896).
May function in skin immunity (PubMed:15184896).
Enhances myeloid progenitor cell survival in vitro (By similarity).
Induces RETNLA and serum amyloid A protein expression in macrophages (By similarity).
Biological Process
Immune system processIEA:UniProtKB-KW
Cellular Location
Secreted

Borgia, F., Custurone, P., Li Pomi, F., Cordiano, R., Alessandrello, C., & Gangemi, S. (2022). IL-31: State of the art for an inflammation-oriented interleukin. International Journal of Molecular Sciences, 23(12), 6507.

Dubin, C., Del Duca, E., & Guttman-Yassky, E. (2021). The IL-4, IL-13 and IL-31 pathways in atopic dermatitis. Expert Review of Clinical Immunology, 17(8), 835-852.

Kunimura, K., & Fukui, Y. (2021). The molecular basis for IL-31 production and IL-31-mediated itch transmission: from biology to drug development. International immunology, 33(12), 731-736.

De Martinis, M., Sirufo, M. M., Suppa, M., & Ginaldi, L. (2020). IL-33/IL-31 axis in osteoporosis. International journal of molecular sciences, 21(4), 1239.

Topal, F. A., Zuberbier, T., Makris, M. P., & Hofmann, M. (2020). The role of IL-17, IL-23 and IL-31, IL-33 in allergic skin diseases. Current opinion in allergy and clinical immunology, 20(4), 367-373.

Murdaca, G., Greco, M., Tonacci, A., Negrini, S., Borro, M., Puppo, F., & Gangemi, S. (2019). IL-33/IL-31 axis in immune-mediated and allergic diseases. International journal of molecular sciences, 20(23), 5856.

Miake, S., Tsuji, G., Takemura, M., Hashimoto-Hachiya, A., Vu, Y. H., Furue, M., & Nakahara, T. (2019). IL-4 augments IL-31/IL-31 receptor alpha interaction leading to enhanced Ccl 17 and Ccl 22 production in dendritic cells: implications for atopic dermatitis. International journal of molecular sciences, 20(16), 4053.

Bağci, I. S., & Ruzicka, T. (2018). IL-31: a new key player in dermatology and beyond. Journal of Allergy and Clinical Immunology, 141(3), 858-866.

Di Salvo, E., Ventura-Spagnolo, E., Casciaro, M., Navarra, M., & Gangemi, S. (2018). IL-33/IL-31 axis: a potential inflammatory pathway. Mediators of inflammation, 2018.

Takamori, A., Nambu, A., Sato, K., Yamaguchi, S., Matsuda, K., Numata, T., ... & Nakae, S. (2018). IL-31 is crucial for induction of pruritus, but not inflammation, in contact hypersensitivity. Scientific Reports, 8(1), 6639.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus Recombinant IL31 protein, His Tag (CAT#: V2LY-0526-LY1569)

Human Recombinant IL31 protein, His & AVI Tag (CAT#: V2LY-0526-LY4888)

Human Recombinant IL31 protein, His & AVI Tag-1 (CAT#: V2LY-0526-LY4889)

Human Recombinant IL31 protein, His Tag (CAT#: V2LY-0526-LY4890)

Human Recombinant IL31 protein, His Tag-1 (CAT#: V2LY-0526-LY4891)

Mouse Recombinant IL31 protein, His Tag (CAT#: V2LY-0526-LY8534)

Rat Recombinant IL31 protein, His Tag (CAT#: V2LY-0526-LY9475)

Rat Recombinant IL31 protein, His Tag-1 (CAT#: V2LY-0526-LY9476)

Rhesus Recombinant IL31 protein, ECD, His Tag (CAT#: V2LY-0526-LY9754)

Mouse Il31 ELISA Kit (CAT#: V2LY-0626-LY1609)

Related Products

Human Recombinant IL31 protein, His Tag-1 (CAT#: V2LY-0526-LY4891)

Mouse Anti-IL31 Recombinant Antibody (B-S31) (CAT#: CBMAB-I1176-YY)

Cynomolgus Recombinant IL31 protein, His Tag (CAT#: V2LY-0526-LY1569)

Mouse Anti-IL31 Recombinant Antibody (A552) (CAT#: CBMAB-AP3965LY)

Human Recombinant IL31 protein, His & AVI Tag (CAT#: V2LY-0526-LY4888)

Human Recombinant IL31 protein, His Tag (CAT#: V2LY-0526-LY4890)

Mouse Anti-IL31 Recombinant Antibody (A551) (CAT#: CBMAB-AP10885LY)

Rat Recombinant IL31 protein, His Tag (CAT#: V2LY-0526-LY9475)

Human Recombinant IL31 protein, His & AVI Tag-1 (CAT#: V2LY-0526-LY4889)

Mouse Recombinant IL31 protein, His Tag (CAT#: V2LY-0526-LY8534)

Isotype control

For research use only. Not intended for any clinical use.

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