Human IL31RA ELISA Kit (V2LY-0626-LY4768)
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Basic Information
- Pre-coated ELISA Plate: 12 wells * 8 detachable strips
- Standard solution: 0.5ml x1
- Standard diluent: 3ml x1
- Streptavidin-HRP: 6ml x1
- Stop solution: 6ml x1
- Substrate solution A: 6ml x1
- Substrate solution B: 6ml x1
- Wash buffer concentrate (25x): 20ml x1
- Biotinylated antibody: 1ml x1
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
May function in skin immunity (PubMed:15184896).
Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity).
Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).
Cytokine-mediated signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Defense response1 PublicationNAS:UniProtKB
Defense response to other organismIEA:Ensembl
Glandular epithelial cell differentiationIEA:Ensembl
Homeostatic process1 PublicationNAS:UniProtKB
Macrophage differentiation1 PublicationNAS:UniProtKB
MAPK cascade1 PublicationNAS:UniProtKB
Monocyte differentiationManual Assertion Based On ExperimentIEP:UniProtKB
Negative regulation of apoptotic process1 PublicationNAS:UniProtKB
Negative regulation of macrophage activation1 PublicationNAS:UniProtKB
Positive regulation of cell population proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of transcription, DNA-templated1 PublicationNAS:UniProtKB
Positive regulation of tyrosine phosphorylation of STAT proteinManual Assertion Based On ExperimentIEP:UniProtKB
Receptor signaling pathway via JAK-STATManual Assertion Based On ExperimentIEP:UniProtKB
Transmembrane receptor protein tyrosine kinase signaling pathway1 PublicationNAS:UniProtKB
A primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually presents with itching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening that may be exacerbated by chronic scratching and rubbing. Primary localized cutaneous amyloidosis is often divided into macular and lichen subtypes although many affected individuals often show both variants coexisting. Lichen amyloidosis characteristically presents as a pruritic eruption of grouped hyperkeratotic papules with a predilection for the shins, calves, ankles and dorsa of feet and thighs. Papules may coalesce to form hyperkeratotic plaques that can resemble lichen planus, lichen simplex or nodular prurigo. Macular amyloidosis is characterized by small pigmented macules that may merge to produce macular hyperpigmentation, sometimes with a reticulate or rippled pattern. In macular and lichen amyloidosis, amyloid is deposited in the papillary dermis in association with grouped colloid bodies, thought to represent degenerate basal keratinocytes. The amyloid deposits probably reflect a combination of degenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins.
Helical: 520-540
Cytoplasmic: 541-732
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
IL31RA Matched Antibody Pair (633) (CAT#: APMAB-633LY)
Cynomolgus Recombinant IL31RA protein, His Tag (CAT#: V2LY-0526-LY1571)
Human Recombinant IL31RA protein, ECD, hFc Tag (CAT#: V2LY-0526-LY4892)
Human Recombinant IL31RA protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY4893)
Human Recombinant IL31RA protein, His Tag (CAT#: V2LY-0526-LY4894)
Human Recombinant IL31RA protein, His Tag-1 (CAT#: V2LY-0526-LY4895)
Mouse Recombinant IL31RA protein, ECD, hFc Tag (CAT#: V2LY-0526-LY8535)
Mouse Recombinant IL31RA protein, His Tag (CAT#: V2LY-0526-LY8536)
Rabbit Recombinant IL31RA protein, His Tag (CAT#: V2LY-0526-LY9136)
Antibody Pairs
IL31RA Matched Antibody Pair (633) (CAT#: APMAB-633LY)
Related Products
Rabbit Recombinant IL31RA protein, His Tag (CAT#: V2LY-0526-LY9136)
Human Recombinant IL31RA protein, His Tag (CAT#: V2LY-0526-LY4894)
Rat Recombinant IL31RA protein, His Tag (CAT#: V2LY-0526-LY9477)
IL31RA Matched Antibody Pair (633) (CAT#: APMAB-633LY)
Mouse Anti-IL31RA Recombinant Antibody (3A10) (CAT#: CBMAB-A4405-LY)
Human Recombinant IL31RA protein, ECD, hFc Tag (CAT#: V2LY-0526-LY4892)
Human Recombinant IL31RA protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY4893)
Human Recombinant IL31RA protein, His Tag-1 (CAT#: V2LY-0526-LY4895)
Cynomolgus Recombinant IL31RA protein, His Tag (CAT#: V2LY-0526-LY1571)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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