Human LY96 ELISA Kit (V2LY-0626-LY4839)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.024 ng/mL
Detection Range
0.05-10 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
18.5 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
LY96
Function
Binds bacterial lipopolysaccharide (LPS) (PubMed:17803912, PubMed:17569869).
Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria (PubMed:11160242, PubMed:11593030).
Enhances TLR4-dependent activation of NF-kappa-B (PubMed:10359581).
Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10359581).
Biological Process
Cell surface receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Cellular defense responseManual Assertion Based On ExperimentTAS:ProtInc
Cellular response to lipopolysaccharideManual Assertion Based On ExperimentIBA:GO_Central
Detection of lipopolysaccharideManual Assertion Based On ExperimentIDA:UniProtKB
Inflammatory responseIEA:UniProtKB-KW
Innate immune response1 PublicationIC:ComplexPortal
Positive regulation of lipopolysaccharide-mediated signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of tumor necrosis factor productionISS:UniProtKB
Response to lipopolysaccharideManual Assertion Based On ExperimentIDA:MGI
Toll-like receptor 4 signaling pathwayISS:UniProtKB
Toll-like receptor signaling pathwayManual Assertion Based On ExperimentIDA:ComplexPortal
Cellular Location
Secreted, extracellular space
Secreted
Retained in the extracellular space at the cell surface by interaction with TLR4 (PubMed:10359581).
PTM
N-glycosylated; high-mannose.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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