Human MMP19 ELISA Kit (V2LY-0626-LY4868)

Name: Human MMP19 ELISA Kit
SKU: V2LY-0626-LY4868
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.034 ng/mL

Detection Range

0.07-15 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Human

Assay Type

Sandwich

Reactivity

Human

Assay Time

1.5 h

Molecule Mass

57.4 kDa

Components

Pre-coated ELISA Plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

matrix metalloproteinase-19 isoform X2

Function

Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.

Biological Process

Angiogenesis Source: UniProtKB-KW
Cell differentiation Source: UniProtKB-KW
Collagen catabolic process Source: GO_Central
Extracellular matrix disassembly Source: Reactome
Extracellular matrix organization Source: GO_Central
Luteolysis Source: Ensembl
Ovarian follicle development Source: Ensembl
Ovulation from ovarian follicle Source: Ensembl
Proteolysis Source: UniProtKB
Response to cAMP Source: Ensembl
Response to hormone Source: Ensembl

Cellular Location

Extracellular matrix

Involvement in disease

Cavitary optic disc anomalies (CODA):
An ocular disease characterized by a profound excavation of the optic nerve. Clinical phenotype is variable and includes congenitally excavated optic nerves as well as other features of optic pit, optic nerve coloboma, and morning glory disk anomaly. Patients with CODA have a strong predilection for retinal detachment and/or separation of the retinal layers (retinoschisis) that lead to profound central vision loss.

PTM

Activated by autolytic cleavage after Lys-97.
Tyrosine phosphorylated by PKDCC/VLK.

Chen, Z., Wu, G., Ye, F., Chen, G., Fan, Q., Dong, H., ... & Wu, C. (2019). High expression of MMP19 is associated with poor prognosis in patients with colorectal cancer. Bmc Cancer, 19(1), 1-9.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant MMP19 protein (CAT#: V2LY-0526-LY5614)

Mouse Mmp19 ELISA Kit (CAT#: V2LY-0626-LY2610)

Related Products

Human Recombinant MMP19 protein (CAT#: V2LY-0526-LY5614)

Mouse Mmp19 ELISA Kit (CAT#: V2LY-0626-LY2610)

Mouse Anti-MMP19 Recombinant Antibody (CBCNM-026) (CAT#: CBMAB-R0586-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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