Human MTBP ELISA Kit (V2LY-0626-LY5916)

Name: Human MTBP ELISA Kit
SKU: V2LY-0626-LY5916
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.092 ng/mL

Detection Range

0.2-60 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Human

Assay Type

Sandwich

Reactivity

Human

Assay Time

1.5 h

Molecule Mass

102.2 kDa

Components

Pre-coated ELISA plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

MDM2 Binding Protein

Function

Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity).

May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.

Biological Process

Cell cycle Source: UniProtKB-KW
Negative regulation of cell population proliferation Source: Ensembl
Negative regulation of mitotic nuclear division Source: Ensembl
Protein localization to kinetochore Source: MGI
Regulation of protein ubiquitination Source: InterPro
Traversing start control point of mitotic cell cycle Source: GO_Central

Cellular Location

Chromatin
Kinetochore

Ferreira, P., Höfer, V., Kronshage, N., Marko, A., Reusswig, K. U., Tetik, B., ... & Boos, D. (2021). MTBP phosphorylation controls DNA replication origin firing. Scientific reports, 11(1), 4242.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-MTBP Recombinant Antibody (A1198) (CAT#: CBMAB-AP4877LY)

Recombinant Mouse Anti-MTBP Recombinant Antibody (2C1G6) (CAT#: CBMAB-XB0838-YC)

Mouse Anti-MTBP (AA 1-425) Recombinant Antibody (CBFYM-2720) (CAT#: CBMAB-M2913-FY)

Mouse Anti-MTBP (N-terminus) Recombinant Antibody (CBFYM-2721) (CAT#: CBMAB-M2914-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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