Human NRP2 ELISA Kit (V2LY-0626-LY4950)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.045 ng/mL
Detection Range
0.1-40 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
104.8 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
neuropilin 2
Function
High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.
(Microbial infection) Acts as a receptor for human cytomegalovirus pentamer-dependent entry in epithelial and endothelial cells.
Biological Process
Angiogenesis1 PublicationNAS:UniProtKB
Axon extension involved in axon guidanceISS:BHF-UCL
Axon guidanceManual Assertion Based On ExperimentTAS:ProtInc
Cell adhesion1 PublicationNAS:UniProtKB
Cellular response to leukemia inhibitory factorIEA:Ensembl
Dorsal root ganglion morphogenesisIEA:Ensembl
Facial nerve structural organizationIEA:Ensembl
Facioacoustic ganglion developmentIEA:Ensembl
Gonadotrophin-releasing hormone neuronal migration to the hypothalamusIEA:Ensembl
Negative chemotaxisIEA:Ensembl
Nerve developmentISS:BHF-UCL
Neural crest cell migration involved in autonomic nervous system developmentIEA:Ensembl
Outflow tract septum morphogenesisISS:BHF-UCL
Positive regulation of endothelial cell migrationManual Assertion Based On ExperimentTAS:BHF-UCL
Positive regulation of endothelial cell proliferationManual Assertion Based On ExperimentTAS:BHF-UCL
Regulation of postsynapse organizationIEA:Ensembl
Semaphorin-plexin signaling pathway involved in neuron projection guidanceISS:BHF-UCL
Sensory neuron axon guidanceIEA:Ensembl
Sympathetic ganglion developmentISS:BHF-UCL
Sympathetic neuron projection extensionISS:BHF-UCL
Sympathetic neuron projection guidanceISS:BHF-UCL
Trigeminal ganglion developmentIEA:Ensembl
Ventral trunk neural crest cell migrationIEA:Ensembl
Vestibulocochlear nerve structural organizationIEA:Ensembl
Cellular Location
Membrane
Isoform s9
Secreted
Topology
Extracellular: 21-864
Helical: 865-889
Cytoplasmic: 890-931

Immormino, R. M., Jania, C. M., Tilley, S. L., & Moran, T. P. (2022). Neuropilin‐2 regulates airway inflammation in a neutrophilic asthma model. Immunity, Inflammation and Disease, 10(3), e575.

Wang, J., Li, J., Yin, L., Pu, T., Wei, J., Karthikeyan, V., ... & Wu, B. J. (2022). Neuropilin-2 promotes lineage plasticity and progression to neuroendocrine prostate cancer. Oncogene, 41(37), 4307-4317.

Lungulescu, C., Ghimpau, V., Gheonea, D. I., Sur, D., & Lungulescu, C. V. (2022). The Role of neuropilin-2 in the epithelial to mesenchymal transition of colorectal cancer: A systematic review. Biomedicines, 10(1), 172.

Islam, R., Mishra, J., Bodas, S., Bhattacharya, S., Batra, S. K., Dutta, S., & Datta, K. (2022). Role of Neuropilin-2-mediated signaling axis in cancer progression and therapy resistance. Cancer and Metastasis Reviews, 41(3), 771-787.

Dumond, A., Brachet, E., Durivault, J., Vial, V., Puszko, A. K., Lepelletier, Y., ... & Pagès, G. (2021). Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinoma. Journal of experimental & clinical cancer research, 40, 1-18.

Dumond, A., & Pagès, G. (2021). Relevance of neuropilin 1 and neuropilin 2 targeting for cancer treatment. Journal of Cancer Immunology, 3(2), 111-114.

Lee, G., Kang, Y. E., Oh, C., Liu, L., Jin, Y., Lim, M. A., ... & Koo, B. S. (2020). Neuropilin-2 promotes growth and progression of papillary thyroid cancer cells. Auris Nasus Larynx, 47(5), 870-880.

Borkowetz, A., Froehner, M., Rauner, M., Conrad, S., Erdmann, K., Mayr, T., ... & Muders, M. H. (2020). Neuropilin‐2 is an independent prognostic factor for shorter cancer‐specific survival in patients with acinar adenocarcinoma of the prostate. International journal of cancer, 146(9), 2619-2627.

Harman, J. L., Sayers, J., Chapman, C., & Pellet-Many, C. (2020). Emerging roles for neuropilin-2 in cardiovascular disease. International Journal of Molecular Sciences, 21(14), 5154.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant NRP2 protein, hFc Tag (CAT#: V2LY-0526-LY5774)

Human Recombinant NRP2 protein, His Tag (CAT#: V2LY-0526-LY5775)

Mouse Recombinant NRP2 protein, His Tag (CAT#: V2LY-0526-LY8701)

Rat Nrp2 ELISA Kit (CAT#: V2LY-0626-LY2467)

Related Products

Human Recombinant NRP2 protein, His Tag (CAT#: V2LY-0526-LY5775)

Mouse Recombinant NRP2 protein, His Tag (CAT#: V2LY-0526-LY8701)

Mouse Anti-NRP2 Recombinant Antibody (M391) (CAT#: CBMAB-N3626-WJ)

Rabbit Anti-NRP2 Recombinant Antibody (D39A5) (CAT#: CBMAB-N3625-WJ)

Mouse Anti-NRP2 Recombinant Antibody (CBWJN-1033) (CAT#: CBMAB-N0539-WJ)

Mouse Anti-NRP2 Recombinant Antibody (CBWJN-1031) (CAT#: CBMAB-N0537-WJ)

Rat Nrp2 ELISA Kit (CAT#: V2LY-0626-LY2467)

Mouse Anti-NRP2 Recombinant Antibody (CBWJN-1556) (CAT#: CBMAB-N3622-WJ)

Mouse Anti-NRP2 Recombinant Antibody (CBWJN-1032) (CAT#: CBMAB-N0538-WJ)

Mouse Anti-NRP2 Recombinant Antibody (CBWJN-1555) (CAT#: CBMAB-N3621-WJ)

Isotype control

For research use only. Not intended for any clinical use.

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