loading...

NRP2

This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Full Name

neuropilin 2

Function

High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.
(Microbial infection) Acts as a receptor for human cytomegalovirus pentamer-dependent entry in epithelial and endothelial cells.

Biological Process

Angiogenesis1 PublicationNAS:UniProtKB
Axon extension involved in axon guidanceISS:BHF-UCL
Axon guidanceManual Assertion Based On ExperimentTAS:ProtInc
Cell adhesion1 PublicationNAS:UniProtKB
Cellular response to leukemia inhibitory factorIEA:Ensembl
Dorsal root ganglion morphogenesisIEA:Ensembl
Facial nerve structural organizationIEA:Ensembl
Facioacoustic ganglion developmentIEA:Ensembl
Gonadotrophin-releasing hormone neuronal migration to the hypothalamusIEA:Ensembl
Negative chemotaxisIEA:Ensembl
Nerve developmentISS:BHF-UCL
Neural crest cell migration involved in autonomic nervous system developmentIEA:Ensembl
Outflow tract septum morphogenesisISS:BHF-UCL
Positive regulation of endothelial cell migrationManual Assertion Based On ExperimentTAS:BHF-UCL
Positive regulation of endothelial cell proliferationManual Assertion Based On ExperimentTAS:BHF-UCL
Regulation of postsynapse organizationIEA:Ensembl
Semaphorin-plexin signaling pathway involved in neuron projection guidanceISS:BHF-UCL
Sensory neuron axon guidanceIEA:Ensembl
Sympathetic ganglion developmentISS:BHF-UCL
Sympathetic neuron projection extensionISS:BHF-UCL
Sympathetic neuron projection guidanceISS:BHF-UCL
Trigeminal ganglion developmentIEA:Ensembl
Ventral trunk neural crest cell migrationIEA:Ensembl
Vestibulocochlear nerve structural organizationIEA:Ensembl

Cellular Location

Membrane
Isoform s9
Secreted

Topology

Extracellular: 21-864
Helical: 865-889
Cytoplasmic: 890-931

View more

Anti-NRP2 antibodies

+ Filters

Loading...

Rabbit Anti-NRP2 Recombinant Antibody (D39A5) (CBMAB-N3625-WJ)

Compare

Target: NRP2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Rat

Clone: D39A5

Application*: WB, IP, P, IF

Mouse Recombinant NRP2 protein, His Tag (V2LY-0526-LY8701)

Compare

Target: NRP2

Expressed Host: HEK293 Cells

Sequence: Amino Acid: 1-864

Tag: His Tag

Human Recombinant NRP2 protein, His Tag (V2LY-0526-LY5775)

Compare

Target: NRP2

Expressed Host: HEK293 Cells

Sequence: Amino Acid: 1-855

Tag: His Tag

Human Recombinant NRP2 protein, hFc Tag (V2LY-0526-LY5774)

Compare

Target: NRP2

Expressed Host: HEK293 Cells

Sequence: Amino Acid: 1-855

Tag: hFc Tag

Mouse Anti-NRP2 Recombinant Antibody (M391) (CBMAB-N3626-WJ)

Compare

Target: NRP2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Rat, Mouse

Clone: M391

Application*: WB, E

Mouse Anti-NRP2 Recombinant Antibody (3B8) (CBMAB-N3624-WJ)

Compare

Target: NRP2

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3B8

Application*: E, WB

Mouse Anti-NRP2 Recombinant Antibody (2A4H7C11) (CBMAB-N3623-WJ)

Compare

Target: NRP2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2A4H7C11

Application*: E, ED

Mouse Anti-NRP2 Recombinant Antibody (CBWJN-1556) (CBMAB-N3622-WJ)

Compare

Target: NRP2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBWJN-1556

Application*: WB

Mouse Anti-NRP2 Recombinant Antibody (CBWJN-1555) (CBMAB-N3621-WJ)

Compare

Target: NRP2

Host: Mouse

Specificity: Human

Clone: CBWJN-1555

Application*: EC

Mouse Anti-NRP2 Recombinant Antibody (CBWJN-1033) (CBMAB-N0539-WJ)

Compare

Target: NRP2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBWJN-1033

Application*: F, MC

Mouse Anti-NRP2 Recombinant Antibody (CBWJN-1032) (CBMAB-N0538-WJ)

Compare

Target: NRP2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Mouse, Rat

Clone: CBWJN-1032

Application*: WB, F, MC

Mouse Anti-NRP2 Recombinant Antibody (CBWJN-1031) (CBMAB-N0537-WJ)

Compare

Target: NRP2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBWJN-1031

Application*: F

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry