Human NTF4 ELISA Kit (V2LY-0626-LY1547)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.025 ng/mL
Detection Range
0.05-10 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
22.4 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Neurotrophin 4
Function
Target-derived survival factor for peripheral sensory sympathetic neurons.
Biological Process
Adult locomotory behaviorBy SimilarityISS:UniProtKB
Epidermis developmentBy SimilarityISS:UniProtKB
Ganglion mother cell fate determinationBy SimilarityISS:UniProtKB
InnervationIEA:Ensembl
Long-term memoryBy SimilarityISS:UniProtKB
Mechanoreceptor differentiationIEA:Ensembl
MemoryManual Assertion Based On ExperimentIBA:GO_Central
Modulation of chemical synaptic transmissionManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of neuron apoptotic processManual Assertion Based On ExperimentIBA:GO_Central
Nerve developmentManual Assertion Based On ExperimentIBA:GO_Central
Nerve growth factor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Neuron projection morphogenesisManual Assertion Based On ExperimentIBA:GO_Central
Peripheral nervous system developmentManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of peptidyl-serine phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Sensory organ boundary specificationBy SimilarityISS:UniProtKB
Taste bud developmentIEA:Ensembl
Transmembrane receptor protein tyrosine kinase signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
Involvement in disease
Glaucoma 1, open angle, O (GLC1O):
A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. However, glaucoma can occur at any intraocular pressure. The disease is generally asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.

Sun, R., He, J., Xiang, Q., Feng, Y., Gong, Y., Ning, Y., ... & Xiang, T. (2023). NTF4 plays a dual role in breast cancer in mammary tumorigenesis and metastatic progression. International Journal of Biological Sciences, 19(2), 641.

Mu, L., Zhao, H., Zhang, Y., & Xiao, C. (2022). The Role of Neurotrophin-4/Forkhead Box L1 in the Development of Nonsmall-Cell Lung Cancer. Contrast Media & Molecular Imaging, 2022.

Omar, N. A., Kumar, J., & Teoh, S. L. (2022). Neurotrophin-3 and neurotrophin-4: The unsung heroes that lies behind the meninges. Neuropeptides, 92, 102226.

Yang, Z., Chen, Y., Wei, X., Wu, D., Min, Z., & Quan, Y. (2020). Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy. International Journal of Oncology, 56(6), 1442-1454.

Balim, D. Y., Ay, O. I., Ay, M. E., Karakas, U., Kenar, A. I., & Erdal, M. E. (2019). Are brain derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 gene expression changes effective in the pathogenesis of major depression?/Beyin kokenli norotrofik faktor, norotrofin-3 ve norotrofin-4 gen ekspresyon degisimleri major depresyonun patogenezinde etkili midir?. Anadolu Psikiyatri Dergisi, 20(6), 581-589.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant NTF4 protein (CAT#: V2LY-0526-LY5851)

Mouse Ntf4 ELISA Kit (CAT#: V2LY-0626-LY326)

Rat Ntf4 ELISA Kit (CAT#: V2LY-0626-LY948)

Related Products

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Mouse Anti-NTF4 Recombinant Antibody (NYRhNT-4) (CAT#: CBMAB-N3737-WJ)

Mouse Anti-NTF4 Recombinant Antibody (CBWJN-0679) (CAT#: CBMAB-N3735-WJ)

Mouse Anti-NTF4 Recombinant Antibody (1G12) (CAT#: CBMAB-N3728-WJ)

Mouse Ntf4 ELISA Kit (CAT#: V2LY-0626-LY326)

Mouse Anti-NTF4 Recombinant Antibody (PEPY051_hNT-4) (CAT#: CBMAB-N3738-WJ)

Mouse Anti-NTF4 Recombinant Antibody (CBWJN-1568) (CAT#: CBMAB-N3724-WJ)

Mouse Anti-NTF4 Recombinant Antibody (5C81) (CAT#: CBMAB-N0549-WJ)

Mouse Anti-NTF4 Recombinant Antibody (CBWJN-1567) (CAT#: CBMAB-N3723-WJ)

Isotype control

For research use only. Not intended for any clinical use.

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