Human PKP2 ELISA Kit (V2LY-0626-LY2856)

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Tested Data
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Basic Information

Sensitivity
0.0052 ng/mL
Detection Range
0.01-2 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
97.4 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
plakophilin 2
Function
May play a role in junctional plaques.
Biological Process
Bundle of His cell-Purkinje myocyte adhesion involved in cell communicationManual Assertion Based On ExperimentIMP:BHF-UCL
Cardiac muscle cell action potential involved in contractionManual Assertion Based On ExperimentIMP:BHF-UCL
Cell communication by electrical coupling involved in cardiac conductionISS:BHF-UCL
Cell-cell adhesionISS:BHF-UCL
Cell-cell junction assemblyManual Assertion Based On ExperimentIBA:GO_Central
Cell-cell signaling involved in cardiac conductionManual Assertion Based On ExperimentIMP:BHF-UCL
Desmosome assemblyManual Assertion Based On ExperimentIMP:BHF-UCL
Desmosome organizationManual Assertion Based On ExperimentIBA:GO_Central
Heart developmentISS:BHF-UCL
Intermediate filament bundle assemblyManual Assertion Based On ExperimentIMP:BHF-UCL
Maintenance of animal organ identityManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of sodium ion transportISS:BHF-UCL
Protein localization to plasma membraneManual Assertion Based On ExperimentIMP:BHF-UCL
Regulation of heart rate by cardiac conductionManual Assertion Based On ExperimentIMP:BHF-UCL
Regulation of ventricular cardiac muscle cell action potentialManual Assertion Based On ExperimentIMP:BHF-UCL
Ventricular cardiac muscle cell action potentialManual Assertion Based On ExperimentIMP:BHF-UCL
Ventricular cardiac muscle tissue morphogenesisManual Assertion Based On ExperimentIMP:BHF-UCL
Cellular Location
Nucleus
Cell junction, desmosome
Nuclear and associated with desmosomes.
Involvement in disease
Arrhythmogenic right ventricular dysplasia, familial, 9 (ARVD9):
A congenital heart disease characterized by infiltration of adipose and fibrous tissue into the right ventricle and loss of myocardial cells, resulting in ventricular and supraventricular arrhythmias.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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