Human PLS1 ELISA Kit (V2LY-0626-LY5602)

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Tested Data
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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.017 ng/mL
Detection Range
0.05-15 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
70.3 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
plastin 1 (I isoform)
Function
Actin-bundling protein. In the inner ear, it is required for stereocilia formation. Mediates liquid packing of actin filaments that is necessary for stereocilia to grow to their proper dimensions.
Biological Process
Actin filament bundle assemblyManual Assertion Based On ExperimentIBA:GO_Central
Actin filament network formationManual Assertion Based On ExperimentIBA:GO_Central
Auditory receptor cell stereocilium organizationISS:UniProtKB
Intestinal D-glucose absorptionIEA:Ensembl
Positive regulation of multicellular organism growthIEA:Ensembl
Positive regulation of protein localization to plasma membraneISS:UniProtKB
Regulation of microvillus lengthIEA:Ensembl
Terminal web assemblyIEA:Ensembl
Vestibular receptor cell stereocilium organizationISS:UniProtKB
Cellular Location
Cytoplasm
Cell projection, stereocilium
Involvement in disease
Deafness, autosomal dominant, 76 (DFNA76):
A form of non-syndromic deafness characterized by mild to profound sensorineural hearing loss and variable age at onset. Sensorineural hearing loss results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
PTM
Phosphorylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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