Human Recombinant CXCL4 protein (V2LY-0526-LY3436)

Name: Human Recombinant CXCL4 protein
SKU: V2LY-0526-LY3436
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

E. coli

Protein Species

Human

Protein Construction

This product is Human Recombinant CXCL4 protein consist of Amino Acid: 32-101 and predicts a molecular mass of 7.8 kDa.

Molecule Mass

7.8 kDa

Sequence

Amino Acid: 32-101

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>80% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

platelet factor 4

Function

Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.

Biological Process

Adenylate cyclase-activating G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Antimicrobial humoral immune response mediated by antimicrobial peptideManual Assertion Based On ExperimentIDA:UniProtKB
Cellular response to lipopolysaccharideManual Assertion Based On ExperimentIBA:GO_Central
Chemokine-mediated signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cytokine-mediated signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Defense response to protozoanManual Assertion Based On ExperimentIDA:UniProtKB
Inflammatory responseManual Assertion Based On ExperimentIBA:GO_Central
Killing by host of symbiont cellsManual Assertion Based On ExperimentIDA:UniProtKB
Killing of cells of another organismIDA:UniProtKB
Leukocyte chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of angiogenesisManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of extrinsic apoptotic signaling pathway in absence of ligandManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of megakaryocyte differentiationManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of MHC class II biosynthetic processManual Assertion Based On ExperimentIDA:BHF-UCL
Neutrophil chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Platelet activationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of gene expressionManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of macrophage derived foam cell differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of macrophage differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of tumor necrosis factor productionManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of cell population proliferationManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Secreted

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Recombinant CXCL4 protein, His Tag (CAT#: V2LY-0526-LY8179)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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