Human Recombinant NELL2 protein, His Tag (V2LY-0526-LY5745)

Kiyozumi, D. (2024). Expression of NELL2/NICOL-ROS1 lumicrine signaling-related molecules in the human male reproductive tract. Reproductive Biology and Endocrinology, 22(1), 3.

Ha, C. M., Kim, D. H., Lee, T. H., Kim, H. R., Choi, J., Kim, Y., ... & Lee, B. J. (2022). Transcriptional regulatory role of NELL2 in preproenkephalin gene expression. Molecules and cells, 45(8), 537.

Kiyozumi, D. (2022). The molecular mechanisms of mammalian sperm maturation regulated by NELL2-ROS1 lumicrine signaling. The Journal of Biochemistry, 172(6), 341-346.

Wang, Y., Li, M., Zhang, L., Chen, Y., & Zhang, S. (2021). m6A demethylase FTO induces NELL2 expression by inhibiting E2F1 m6A modification leading to metastasis of non-small cell lung cancer. Molecular Therapy-Oncolytics, 21, 367-376.

Jayabal, P., Zhou, F., Lei, X., Ma, X., Blackman, B., Weintraub, S. T., ... & Shiio, Y. (2021). NELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growth. Cell reports, 36(1).

Liu, J., Liu, D., Zhang, X., Li, Y., Fu, X., He, W., ... & Zhang, X. (2021). NELL2 modulates cell proliferation and apoptosis via ERK pathway in the development of benign prostatic hyperplasia. Clinical Science, 135(13), 1591-1608.

Tong, L., Zhang, W., Qu, B., Zhang, F., Wu, Z., Shi, J., ... & Wang, Z. (2021). The tRNA-derived fragment-3017A promotes metastasis by inhibiting NELL2 in human gastric cancer. Frontiers in Oncology, 10, 570916.

Kiyozumi, D., Noda, T., Yamaguchi, R., Tobita, T., Matsumura, T., Shimada, K., ... & Ikawa, M. (2020). NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility. Science, 368(6495), 1132-1135.

Pak, J. S., DeLoughery, Z. J., Wang, J., Acharya, N., Park, Y., Jaworski, A., & Özkan, E. (2020). NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance. Nature Communications, 11(1), 1489.

Taroc, E. Z. M., Lin, J. M., Tulloch, A. J., Jaworski, A., & Forni, P. E. (2019). GnRH-1 neural migration from the nose to the brain is independent from Slit2, Robo3 and NELL2 signaling. Frontiers in Cellular Neuroscience, 13, 70.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols