NELL2

The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis. [provided by RefSeq, Feb 2009]
Full Name
Neural EGFL Like 2
Function
Required for neuron survival through the modulation of MAPK pathways (By similarity).

Involved in the regulation of hypothalamic GNRH secretion and the control of puberty (By similarity).
Biological Process
Fertilization Source: UniProtKB
Neuron cellular homeostasis Source: UniProtKB
Cellular Location
Secreted
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Anti-NELL2 antibodies

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Human Recombinant NELL2 protein, His Tag (V2LY-0526-LY5745)

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Target: NELL2
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-816
Tag: His Tag
Datasheet SDS

Mouse Anti-NELL2 Recombinant Antibody (A1319) (CBMAB-AP5026LY)

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Target: NELL2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse
Clone: A1319
Application*: Dot blot, ELISA, WB
Datasheet SDS

Rabbit Anti-NELL2 Recombinant Antibody (CBWJN-1328) (CBMAB-N1967-WJ)

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Target: NELL2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJN-1328
Application*: WB, IP
Datasheet SDS

Mouse Anti-NELL2 Recombinant Antibody (2D11) (CBMAB-N1965-WJ)

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Target: NELL2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2D11
Application*: E
Datasheet SDS

Mouse Anti-NELL2 Recombinant Antibody (1F6) (CBMAB-N1964-WJ)

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Target: NELL2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1F6
Application*: E, WB
Datasheet SDS

Mouse Anti-NELL2 Recombinant Antibody (CBWJN-0113) (CBMAB-N1963-WJ)

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Target: NELL2
Host: Mouse
Specificity: Human, Mouse
Clone: CBWJN-0113
Application*: E, WB
Datasheet SDS

Rabbit Anti-NELL2 Recombinant Antibody (CBWJN-1326) (CBMAB-N1962-WJ)

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Target: NELL2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJN-1326
Application*: E
Datasheet SDS

Mouse Anti-NELL2 Recombinant Antibody (CBWJN-1325) (CBMAB-N1961-WJ)

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Target: NELL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-1325
Application*: E
Datasheet SDS

Mouse Anti-NELL2 Recombinant Antibody (CBWJN-0973) (CBMAB-N0250-WJ)

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Target: NELL2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse
Clone: CBWJN-0973
Application*: WB, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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