Human Recombinant PHGDH protein, His Tag (V2LY-0526-LY6140)

Name: Human Recombinant PHGDH protein, His Tag
SKU: V2LY-0526-LY6140
Rating: 5 (1 reviews)

See all PHGDH antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

E. coli

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant PHGDH protein, His Tag consist of Amino Acid: 1-533 and predicts a molecular mass of 58 kDa.

Molecule Mass

58 kDa

Sequence

Amino Acid: 1-533

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>90% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Phosphoglycerate Dehydrogenase

Function

Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate.

Biological Process

Brain developmentManual Assertion Based On ExperimentTAS:ProtInc
G1 to G0 transitionIEA:Ensembl
Gamma-aminobutyric acid metabolic processIEA:Ensembl
Glial cell developmentIEA:Ensembl
Glutamine metabolic processIEA:Ensembl
Glycine metabolic processIEA:Ensembl
L-serine biosynthetic processIEA:UniProtKB-KW
Neural tube developmentIEA:Ensembl
Neuron projection developmentIEA:Ensembl
Regulation of gene expressionIEA:Ensembl
Spinal cord developmentIEA:Ensembl
Taurine metabolic processIEA:Ensembl
Threonine metabolic processIEA:Ensembl

Cellular Location

cytosol
extracellular exosome

Involvement in disease

Phosphoglycerate dehydrogenase deficiency (PHGDHD):
An autosomal recessive inborn error of L-serine biosynthesis, clinically characterized by congenital microcephaly, psychomotor retardation, and seizures.
Neu-Laxova syndrome 1 (NLS1):
A lethal, autosomal recessive multiple malformation syndrome characterized by ichthyosis, marked intrauterine growth restriction, microcephaly, short neck, limb deformities, hypoplastic lungs, edema, and central nervous system anomalies including lissencephaly, cerebellar hypoplasia and/or abnormal/agenesis of the corpus callosum. Abnormal facial features include severe proptosis with ectropion, hypertelorism, micrognathia, flattened nose, and malformed ears.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Human Recombinant PHGDH protein, His Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human PHGDH ELISA Kit (CAT#: V2LY-0626-LY2395)

Related Products

Human PHGDH ELISA Kit (CAT#: V2LY-0626-LY2395)

Mouse Anti-PHGDH Recombinant Antibody (13H3) (CAT#: CBMAB-0824-CN)

Rabbit Anti-PHGDH Recombinant Antibody (D3D5E) (CAT#: CBMAB-CP1954-LY)

Mouse Anti-PHGDH Recombinant Antibody (4A1) (CAT#: CBMAB-P1674-YC)

Mouse Anti-PHGDH Recombinant Antibody (9E5) (CAT#: CBMAB-0829-CN)

Mouse Anti-PHGDH Recombinant Antibody (9E12) (CAT#: CBMAB-0828-CN)

Mouse Anti-PHGDH Recombinant Antibody (5C4) (CAT#: CBMAB-P1676-YC)

Mouse Anti-PHGDH Recombinant Antibody (17C4) (CAT#: CBMAB-0825-CN)

Mouse Anti-PHGDH Recombinant Antibody (13A8) (CAT#: CBMAB-0818-CN)

Mouse Anti-PHGDH Recombinant Antibody (4D12) (CAT#: CBMAB-0826-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry