Human Recombinant PILRA protein (V2LY-0526-LY6181)

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Datasheet
SDS
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Basic Information

Expressed Host
HEK293 Cells
Protein Species
Human
Protein Construction
This product is Human Recombinant PILRA protein consist of Amino Acid: 1-226 and predicts a molecular mass of 24.1 kDa.
Molecule Mass
24.1 kDa
Sequence
Amino Acid: 1-226
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>85% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile Tirs, NaCl, Glycerol, DTT
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
paired immunoglobin-like type 2 receptor alpha
Function
Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6/SHP-1 and PTPN11/SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Receptor for PIANP.
(Microbial infection) Acts as an entry co-receptor for herpes simplex virus 1.
Biological Process
Signal transductionManual Assertion Based On ExperimentIDA:MGI
Cellular Location
Isoform 1
Cell membrane
Isoform 2
Cell membrane
Isoform 3
Secreted
Isoform 4
Secreted
Topology
Extracellular: 20-197
Helical: 198-218
Cytoplasmic: 219-303
PTM
According to PubMed:10660620, N- and O-glycosylated. According to PubMed:10903717, only N-glycosylated.
Phosphorylated on tyrosine residues.
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant PILRA protein, Biotin Conjugated, hFc & AVI Tag (CAT#: V2LY-0526-LY6182)

Human Recombinant PILRA protein, hFc Tag (CAT#: V2LY-0526-LY6183)

Human Recombinant PILRA protein, His Tag (CAT#: V2LY-0526-LY6184)

Mouse Recombinant PILRA protein, His Tag (CAT#: V2LY-0526-LY8780)

Related Products

Rat Anti-PILRA Recombinant Antibody (11C43) (CAT#: CBMAB-P1838-YC)

Human Recombinant PILRA protein, hFc Tag (CAT#: V2LY-0526-LY6183)

Mouse Anti-PILRA Recombinant Antibody (3C2) (CAT#: CBMAB-A6693-LY)

Human Recombinant PILRA protein, His Tag (CAT#: V2LY-0526-LY6184)

Human Recombinant PILRA protein, Biotin Conjugated, hFc & AVI Tag (CAT#: V2LY-0526-LY6182)

Rat Anti-PILRA Recombinant Antibody (36H2) (CAT#: CBMAB-P1840-YC)

Mouse Recombinant PILRA protein, His Tag (CAT#: V2LY-0526-LY8780)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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