Human Recombinant PTS protein, His Tag (V2LY-0526-LY6422)

Name: Human Recombinant PTS protein, His Tag
SKU: V2LY-0526-LY6422
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

E. coli

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant PTS protein, His Tag consist of Amino Acid: 1-145 and predicts a molecular mass of 18.2 kDa.

Molecule Mass

18.2 kDa

Sequence

Amino Acid: 1-145

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>85% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

6-pyruvoyltetrahydropterin synthase

Function

Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

Biological Process

Cellular amino acid metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Central nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Tetrahydrobiopterin biosynthetic processManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

cytoplasm
cytosol
mitochondrion

Involvement in disease

Hyperphenylalaninemia, BH4-deficient, A (HPABH4A):
An autosomal recessive disorder characterized by hyperphenylalaninemia, depletion of the neurotransmitters dopamine and serotonin, and progressive cognitive and motor deficits. Neurological symptoms are unresponsive to the classic phenylalanine-low diet.

PTM

Phosphorylation of Ser-19 is required for maximal enzyme activity.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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