Human Recombinant RBBP4 protein, GST Tag (V2LY-0526-LY6468)

Name: Human Recombinant RBBP4 protein, GST Tag
SKU: V2LY-0526-LY6468
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Human

Tag

GST Tag

Protein Construction

This product is Human Recombinant RBBP4 protein, GST Tag consist of Amino Acid: Full Length and predicts a molecular mass of 75 kDa.

Molecule Mass

75 kDa

Sequence

Amino Acid: Full Length

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

Batch dependent.

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

Tris, NaCl

Preservative

None

Storage

Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

More Infomation

Target

Full Name

RB Binding Protein 4, Chromatin Remodeling Factor

Function

Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.

Biological Process

Biological Process brain development1 PublicationIC:ComplexPortal
Biological Process cell cycleIEA:UniProtKB-KW
Biological Process chromatin assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process chromatin remodelingManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process DNA replicationIEA:UniProtKB-KW
Biological Process DNA replication-dependent chromatin assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process DNA replication-independent chromatin assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process histone deacetylationManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process negative regulation of cell migration1 PublicationIC:ComplexPortal
Biological Process negative regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative regulation of stem cell population maintenance1 PublicationIC:ComplexPortal
Biological Process negative regulation of transcription by RNA polymerase II2 PublicationsIC:ComplexPortal
Biological Process negative regulation of transcription, DNA-templated1 PublicationIC:ComplexPortal
Biological Process negative regulation of transforming growth factor beta receptor signaling pathway1 PublicationIC:ComplexPortal
Biological Process positive regulation of stem cell population maintenance1 PublicationIC:ComplexPortal
Biological Process positive regulation of transcription, DNA-templated1 PublicationIC:ComplexPortal
Biological Process regulation of cell fate specification1 PublicationIC:ComplexPortal
Biological Process regulation of stem cell differentiation1 PublicationIC:ComplexPortal
Biological Process regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:ComplexPortal

Cellular Location

Nucleus
Chromosome, telomere
Localizes to chromatin as part of the PRC2 complex.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant RBBP4 protein, His Tag (CAT#: V2LY-0526-LY6469)

Mouse Recombinant RBBP4 protein, His Tag (CAT#: V2LY-0526-LY8824)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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