Human Recombinant RFK protein, His Tag (V2LY-0526-LY6526)

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Basic Information

Expressed Host
E. coli
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant RFK protein, His Tag consist of Amino Acid: 1-155 and predicts a molecular mass of 19.5 kDa.
Molecule Mass
19.5 kDa
Sequence
Amino Acid: 1-155
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>90% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Liquid
Buffer
PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
Riboflavin Kinase
Function
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.
Biological Process
Biological Process apoptotic processManual Assertion Based On ExperimentIMP:MGI
Biological Process FMN biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process phosphorylationIEA:UniProtKB-KW
Biological Process positive regulation of NAD(P)H oxidase activityManual Assertion Based On ExperimentIMP:MGI
Biological Process reactive oxygen species metabolic processIEA:Ensembl
Biological Process riboflavin biosynthetic process1 PublicationNAS:UniProtKB
Biological Process riboflavin metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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