Human Recombinant RPS6KB2, Active protein, GST Tag (V2LY-0526-LY6611)

Name: Human Recombinant RPS6KB2, Active protein, GST Tag
SKU: V2LY-0526-LY6611
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Human

Tag

GST Tag

Protein Construction

This product is Human Recombinant RPS6KB2, Active protein, GST Tag consist of Amino Acid: Full Length and predicts a molecular mass of 85 kDa.

Molecule Mass

85 kDa

Sequence

Amino Acid: Full Length

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

Batch dependent.

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

PBS, Glycerol, DTT

Preservative

None

Storage

Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

More Infomation

Target

Full Name

RPS6KB2

Function

Phosphorylates specifically ribosomal protein S6 (PubMed:29750193).
Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7 (PubMed:29750193).

Biological Process

Biological Process peptidyl-serine phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of translational initiationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein kinase B signalingIEA:Ensembl
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process TOR signalingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process translationManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Cytoplasm
Nucleus

PTM

Phosphorylated and activated by MTOR. Phosphorylation by PKC within the NLS in response to mitogenic stimuli causes cytoplasmic retention.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

RPS6KB2 Matched Antibody Pair (1016) (CAT#: APMAB-1016LY)

Human Recombinant RPS6KB2 (C150T), Active protein, GST Tag (CAT#: V2LY-0526-LY6609)

Human Recombinant RPS6KB2 protein, GST Tag (CAT#: V2LY-0526-LY6610)

Antibody Pairs

RPS6KB2 Matched Antibody Pair (1016) (CAT#: APMAB-1016LY)

Related Products

Human Recombinant RPS6KB2 protein, GST Tag (CAT#: V2LY-0526-LY6610)

Human Recombinant RPS6KB2 (C150T), Active protein, GST Tag (CAT#: V2LY-0526-LY6609)

Mouse Anti-RPS6KB2 Recombinant Antibody (CBCNR-784) (CAT#: CBMAB-R3590-CN)

Mouse Anti-RPS6KB2 Recombinant Antibody (4B11) (CAT#: CBMAB-R3586-CN)

Mouse Anti-RPS6KB2 Recombinant Antibody (CBCNR-781) (CAT#: CBMAB-R3587-CN)

RPS6KB2 Matched Antibody Pair (1016) (CAT#: APMAB-1016LY)

Mouse Anti-RPS6KB2 Recombinant Antibody (164CT21.2.2) (CAT#: CBMAB-R3585-CN)

Mouse Anti-RPS6KB2 Recombinant Antibody (CBCNR-783) (CAT#: CBMAB-R3589-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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