Human Recombinant SDC1 protein, ECD, APC Conjugated, His Tag (V2LY-0526-LY7032)

Name: Human Recombinant SDC1 protein, ECD, APC Conjugated, His Tag
SKU: V2LY-0526-LY7032
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant SDC1 protein, ECD, APC Conjugated, His Tag consist of Amino Acid: 1-251 and predicts a molecular mass of 27.3 kDa.

Molecule Mass

27.3 kDa

Protein Domain

ECD

Conjugates

APC

Sequence

Amino Acid: 1-251

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Twelve months from date of receipt at -20°C to -70°C in lyophilized form and 3 months at -70°C under sterile conditions after reconstitution. Protect from prolonged exposure to light and avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Syndecan 1

Function

Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).

Biological Process

Biological Process canonical Wnt signaling pathwayIEA:Ensembl
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process inflammatory responseIEA:Ensembl
Biological Process myoblast developmentISS:UniProtKB
Biological Process odontogenesisIEA:Ensembl
Biological Process positive regulation of exosomal secretionManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of extracellular exosome assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process receptor-mediated endocytosisIEA:Ensembl
Biological Process response to calcium ionIEA:Ensembl
Biological Process response to cAMPIEA:Ensembl
Biological Process response to glucocorticoidIEA:Ensembl
Biological Process response to hydrogen peroxideIEA:Ensembl
Biological Process response to toxic substanceIEA:Ensembl
Biological Process Sertoli cell developmentIEA:Ensembl
Biological Process striated muscle cell developmentManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process ureteric bud developmentIEA:Ensembl
Biological Process wound healingIEA:Ensembl

Cellular Location

Membrane
Secreted
Secreted, extracellular exosome
Shedding of the ectodomain produces a soluble form.

Topology

Extracellular: 23-254
Helical: 255-275
Cytoplasmic: 276-310

PTM

Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus Recombinant CD138 protein, hFc Tag (CAT#: V2LY-0526-LY1648)

Human Recombinant SDC1 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY7027)

Human Recombinant SDC1 protein, ECD, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY7028)

Human Recombinant SDC1 protein, ECD, His Tag (CAT#: V2LY-0526-LY7029)

Human Recombinant SDC1 protein, ECD, AF488 Conjugated, His Tag (CAT#: V2LY-0526-LY7030)

Human Recombinant SDC1 protein, ECD, AF647 Conjugated, His Tag (CAT#: V2LY-0526-LY7031)

Human Recombinant SDC1 protein, ECD, PE Conjugated, His Tag (CAT#: V2LY-0526-LY7033)

Mouse Recombinant SDC1 protein, His Tag (CAT#: V2LY-0526-LY8943)

Rat Recombinant SDC1 protein, hFc Tag (CAT#: V2LY-0526-LY9597)

Rat Recombinant SDC1 protein, His Tag (CAT#: V2LY-0526-LY9598)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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