Rat Sdc1 ELISA Kit (V2LY-0626-LY2701)

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Tested Data
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Basic Information

Sensitivity
0.058 ng/mL
Detection Range
0.1-40 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Rat
Assay Type
Sandwich
Reactivity
Rat
Assay Time
1.5 h
Molecule Mass
33.2 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Syndecan 1
Function
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
Biological Process
Biological Process canonical Wnt signaling pathwayIEA:Ensembl
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process inflammatory responseIEA:Ensembl
Biological Process myoblast developmentISS:UniProtKB
Biological Process odontogenesisIEA:Ensembl
Biological Process positive regulation of exosomal secretionManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of extracellular exosome assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process receptor-mediated endocytosisIEA:Ensembl
Biological Process response to calcium ionIEA:Ensembl
Biological Process response to cAMPIEA:Ensembl
Biological Process response to glucocorticoidIEA:Ensembl
Biological Process response to hydrogen peroxideIEA:Ensembl
Biological Process response to toxic substanceIEA:Ensembl
Biological Process Sertoli cell developmentIEA:Ensembl
Biological Process striated muscle cell developmentManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process ureteric bud developmentIEA:Ensembl
Biological Process wound healingIEA:Ensembl
Cellular Location
Membrane
Secreted
Secreted, extracellular exosome
Shedding of the ectodomain produces a soluble form.
Topology
Extracellular: 23-254
Helical: 255-275
Cytoplasmic: 276-310
PTM
Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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