Human Recombinant ST6GAL1 protein, His Tag-2 (V2LY-0526-LY6960)

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Basic Information

Expressed Host
HEK293 Cells
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant ST6GAL1 protein, His Tag consist of Amino Acid: 27-406 and predicts a molecular mass of 46 kDa.
Molecule Mass
46 kDa
Verified
HPLC
Sequence
Amino Acid: 27-406
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
≥90% as determined by SDS-PAGE. ≥90% as determined by SEC-HPLC.
Endotoxin
<0.5 EU/mg protein.
Format
Liquid
Buffer
PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
Function
Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates.
Biological Process
Biological Process humoral immune responseManual Assertion Based On ExperimentTAS:ProtInc
Biological Process N-acetylneuraminate metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of chemotaxisIEA:Ensembl
Biological Process negative regulation of macrophage apoptotic processIEA:Ensembl
Biological Process O-glycan processingTAS:Reactome
Biological Process positive regulation of mononuclear cell proliferationIEA:Ensembl
Biological Process protein N-linked glycosylation via asparagineManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein sialylationIEA:Ensembl
Biological Process regulation of substrate adhesion-dependent cell spreadingIEA:Ensembl
Biological Process response to ethanolIEA:Ensembl
Biological Process sialylationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process viral protein processingTAS:Reactome
Cellular Location
Golgi apparatus, Golgi stack membrane
Secreted
Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
Topology
Cytoplasmic: 1-9
Helical: 10-26
Lumenal: 27-406
PTM
The soluble form derives from the membrane form by proteolytic processing.
The HB-6, CDW75, and CD76 differentiation antigens are cell-surface carbohydrate determinants generated by this enzyme.
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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