Human Recombinant TBCK protein, GST Tag (V2LY-0526-LY7140)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Involved in the regulation of cell proliferation and growth (PubMed:23977024, PubMed:24576458).
Involved in the control of actin-cytoskeleton organization (PubMed:23977024).
Biological Process activation of GTPase activityIBA:GO_Central1 Publication
Biological Process cell population proliferationIMP:UniProtKB1 Publication
Biological Process regulation of TOR signalingIMP:UniProtKB1 Publication
Cytoplasm, cytoskeleton, spindle
Midbody
Mainly localized in the cytoplasm during interphase. During metaphase, TBCK accumulates at the mitotic spindle. At the end of mitosis, it is detected at the midbody.
An autosomal recessive neurodevelopmental disorder characterized by profound developmental disability, intellectual disability and severe hypotonia. Many patients have seizures, and show brain atrophy, dysgenesis of the corpus callosum and white-matter changes on neuroimaging. Non-specific facial dysmorphism is noted in some individuals.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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