Human Recombinant TGFBR3 protein, His Tag (V2LY-0526-LY7188)

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Basic Information

Expressed Host
Baculovirus-Insect Cells
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant TGFBR3 protein, His Tag consist of Amino Acid: 1-781 and predicts a molecular mass of 87.8 kDa.
Molecule Mass
87.8 kDa
Sequence
Amino Acid: 1-781
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
≥90% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
TGFBR3 Gene(Protein Coding) Transforming Growth Factor Beta Receptor 3
Function
Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
Biological Process
Biological Process animal organ regenerationSource:Ensembl
Biological Process BMP signaling pathwaySource:BHF-UCL1 Publication
Biological Process cardiac epithelial to mesenchymal transitionSource:BHF-UCL1 Publication
Biological Process cardiac muscle cell proliferationSource:BHF-UCL
Biological Process cell migrationSource:BHF-UCL
Biological Process definitive erythrocyte differentiationSource:BHF-UCL
Biological Process definitive hemopoiesisSource:BHF-UCL
Biological Process epicardium-derived cardiac fibroblast cell developmentSource:BHF-UCL
Biological Process epithelial to mesenchymal transitionSource:BHF-UCL1 Publication
Biological Process heart morphogenesisSource:BHF-UCL
Biological Process heart trabecula formationSource:BHF-UCL
Biological Process heart trabecula morphogenesisSource:BHF-UCL
Biological Process immune responseSource:BHF-UCL1 Publication
Biological Process intracellular signal transductionSource:BHF-UCL1 Publication
Biological Process liver developmentSource:BHF-UCL
Biological Process muscular septum morphogenesisSource:BHF-UCL
Biological Process negative regulation of epithelial cell proliferationSource:BHF-UCL
Biological Process negative regulation of transforming growth factor beta receptor signaling pathwaySource:Ensembl
Biological Process outflow tract morphogenesisSource:BHF-UCL
Biological Process pathway-restricted SMAD protein phosphorylationSource:BHF-UCL1 Publication
Biological Process positive regulation of cardiac muscle cell proliferationSource:BHF-UCL
Biological Process positive regulation of transforming growth factor beta receptor signaling pathwaySource:Ensembl
Biological Process regulation of protein bindingSource:Ensembl
Biological Process regulation of transforming growth factor beta receptor signaling pathwaySource:GO_Central1 Publication
Biological Process response to follicle-stimulating hormoneSource:BHF-UCL1 Publication
Biological Process response to hypoxiaSource:Ensembl
Biological Process response to luteinizing hormoneSource:BHF-UCL1 Publication
Biological Process response to prostaglandin ESource:BHF-UCL1 Publication
Biological Process secondary palate developmentSource:BHF-UCL
Biological Process transforming growth factor beta receptor complex assemblySource:Ensembl
Biological Process transforming growth factor beta receptor signaling pathwaySource:BHF-UCL1 Publication
Biological Process vasculogenesis involved in coronary vascular morphogenesisSource:BHF-UCL
Biological Process ventricular cardiac muscle tissue morphogenesisSource:BHF-UCL
Biological Process ventricular compact myocardium morphogenesisSource:BHF-UCL
Biological Process ventricular septum morphogenesisSource:BHF-UCL
Cellular Location
Secreted
Secreted, extracellular space
Cell membrane
Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
Topology
Extracellular: 21-787
Helical: 788-809
Cytoplasmic: 810-851
PTM
Extensively modified by glycosaminoglycan groups (GAG).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

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