Human Recombinant VTCN1 protein, ECD, hFc Tag-1 (V2LY-0526-LY2266)

Name: Human Recombinant VTCN1 protein, ECD, hFc Tag-1
SKU: V2LY-0526-LY2266
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Human

Tag

hFc Tag

Protein Construction

This product is Human Recombinant VTCN1 protein, ECD, hFc Tag consist of Amino Acid: 29-258 and predicts a molecular mass of 52.3 kDa.

Molecule Mass

52.3 kDa

Protein Domain

ECD

Verified

HPLC

Sequence

Amino Acid: 29-258

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥90% as determined by SDS-PAGE. ≥90% as determined by SEC-HPLC.

Endotoxin

<0.5 EU/mg protein.

Format

Liquid

Buffer

MOPS, NaCl, Glutathione, DTT, PMSF, Glycerol

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

V-set domain containing T cell activation inhibitor 1

Function

Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.

Biological Process

Biological Process adaptive immune response Source:UniProtKB-KW
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process negative regulation of T cell activation Source:UniProtKB1 Publication
Biological Process negative regulation of T cell proliferation Source:UniProtKB1 Publication
Biological Process positive regulation of interleukin-2 production Source:Ensembl
Biological Process positive regulation of T cell proliferation Source:Ensembl
Biological Process regulation of cytokine production Source:GO_Central1 Publication
Biological Process response to protozoan Source:Ensembl
Biological Process T cell receptor signaling pathway Source:GO_Central1 Publication

Cellular Location

Cell membrane
Expressed at the cell surface. A soluble form has also been detected.

Topology

Extracellular: 25-259
Helical: 260-280
Cytoplasmic: 281-282

PTM

N-glycosylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus, Rhesus Recombinant VTCN1 protein, His Tag (CAT#: V2LY-0526-LY1681)

Human Recombinant VTCN1 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY2265)

Human Recombinant VTCN1 protein, ECD, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY2267)

Human Recombinant VTCN1 protein, ECD, Biotin Conjugated, His & AVI Tag-1 (CAT#: V2LY-0526-LY2268)

Human Recombinant VTCN1 protein, ECD, His Tag (CAT#: V2LY-0526-LY2269)

Human Recombinant VTCN1 protein, ECD, His Tag-1 (CAT#: V2LY-0526-LY2270)

Human Recombinant VTCN1 protein, Biotin Conjugated, hFc Tag (CAT#: V2LY-0526-LY2271)

Human Recombinant VTCN1 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY2272)

Human Recombinant VTCN1 protein, Fc Tag (CAT#: V2LY-0526-LY2273)

Mouse Recombinant VTCN1 protein, hFc Tag (CAT#: V2LY-0526-LY7850)

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Human Recombinant VTCN1 protein, ECD, Biotin Conjugated, His & AVI Tag-1 (CAT#: V2LY-0526-LY2268)

Human Recombinant VTCN1 protein, Biotin Conjugated, hFc Tag (CAT#: V2LY-0526-LY2271)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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