Human RSPO1 ELISA Kit (V2LY-0626-LY5197)
Compare
Online Inquiry
Basic Information
- Pre-coated ELISA Plate: 12 wells * 8 detachable strips
- Standard solution: 0.5ml x1
- Standard diluent: 3ml x1
- Streptavidin-HRP: 6ml x1
- Stop solution: 6ml x1
- Substrate solution A: 6ml x1
- Substrate solution B: 6ml x1
- Wash buffer concentrate (25x): 20ml x1
- Biotinylated antibody: 1ml x1
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination. Regulates Wnt signaling by antagonizing DKK1/KREM1-mediated internalization of LRP6 through an interaction with KREM1 (PubMed:17804805).
Biological Process positive regulation of protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of Wnt signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of receptor internalizationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process Wnt signaling pathwayIEA:UniProtKB-KW
Nucleus
Seems to mainly localize to nucleoli.
A recessive syndrome characterized by XX (female to male) SRY-independent sex reversal, palmoplantar hyperkeratosis and predisposition to squamous cell carcinoma of the skin.
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon
$30 eGift Card
Submit a review
Loading...
Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Human Recombinant RSPO1 protein, His Tag (CAT#: V2LY-0526-LY6623)
Human Recombinant RSPO1 protein (CAT#: V2LY-0526-LY6625)
Mouse Recombinant RSPO1 protein, His Tag (CAT#: V2LY-0526-LY8850)
Mouse Rspo1 ELISA Kit (CAT#: V2LY-0626-LY3003)
Related Products
Mouse Anti-RSPO1 Recombinant Antibody (11A9) (CAT#: CBMAB-R3736-CN)
Human Recombinant RSPO1 protein, His Tag (CAT#: V2LY-0526-LY6623)
Mouse Anti-RSPO1 Recombinant Antibody (7A6) (CAT#: CBMAB-R3743-CN)
Rat Anti-RSPO1 Recombinant Antibody (852010) (CAT#: CBMAB-R3744-CN)
Human Recombinant RSPO1 protein (CAT#: V2LY-0526-LY6625)
Mouse Anti-RSPO1 Recombinant Antibody (2B11) (CAT#: CBMAB-R3740-CN)
Mouse Anti-RSPO1 Recombinant Antibody (13B660) (CAT#: CBMAB-R3737-CN)
Mouse Rspo1 ELISA Kit (CAT#: V2LY-0626-LY3003)
Mouse Anti-RSPO1 Recombinant Antibody (CBT1079) (CAT#: V2LY-0625-LY3050)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
Online InquiryContact us
