Human SLAMF7 ELISA Kit (V2LY-0626-LY5254)
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Basic Information
- Pre-coated ELISA Plate: 12 wells * 8 detachable strips
- Standard solution: 0.5ml x1
- Standard diluent: 3ml x1
- Streptavidin-HRP: 6ml x1
- Stop solution: 6ml x1
- Substrate solution A: 6ml x1
- Substrate solution B: 6ml x1
- Wash buffer concentrate (25x): 20ml x1
- Biotinylated antibody: 1ml x1
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K (PubMed:16339536).
In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells (By similarity).
May play a role in lymphocyte adhesion (PubMed:11802771).
In LPS-activated monocytes negatively regulates production of pro-inflammatory cytokines (PubMed:23695528).
Isoform 3 does not mediate any NK cell activation.
Biological Process cell adhesion1 PublicationNAS:UniProtKB
Biological Process natural killer cell activation1 PublicationNAS:UniProtKB
Biological Process natural killer cell mediated cytotoxicity1 PublicationNAS:UniProtKB
Biological Process T cell activationManual Assertion Based On ExperimentIBA:GO_Central
Helical: 227-247
Cytoplasmic: 248-335
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Human Recombinant SLAMF7 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY6848)
Human Recombinant SLAMF7 protein, Biotin Conjugated, hFc Tag (CAT#: V2LY-0526-LY6850)
Human Recombinant SLAMF7 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY6851)
Human Recombinant SLAMF7 protein, AF488 Conjugated, His Tag (CAT#: V2LY-0526-LY6852)
Human Recombinant SLAMF7 protein, AF647 Conjugated, His Tag (CAT#: V2LY-0526-LY6853)
Human Recombinant SLAMF7 protein, APC Conjugated, His Tag (CAT#: V2LY-0526-LY6854)
Human Recombinant SLAMF7 protein, PE Conjugated, His Tag (CAT#: V2LY-0526-LY6855)
Mouse Recombinant SLAMF7 protein, His Tag (CAT#: V2LY-0526-LY8916)
Related Products
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Human Recombinant SLAMF7 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY6851)
Rat Anti-SLAMF7 Recombinant Antibody (520914) (CAT#: CBMAB-C2969-LY)
Human Recombinant SLAMF7 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY6848)
Rabbit Anti-SLAMF7 Recombinant Antibody (E5C4M) (CAT#: CBMAB-CP2460-LY)
Rat Anti-SLAMF7 Recombinant Antibody (15H35) (CAT#: CBMAB-C3283-LY)
Mouse Anti-SLAMF7 Recombinant Antibody (CBFYC-0321) (CAT#: CBMAB-C0357-FY)
Mouse Anti-SLAMF7 Recombinant Antibody (162.1) (CAT#: CBMAB-C0396-LY)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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