Human SLC30A8 ELISA Kit (V2LY-0626-LY3816)

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Tested Data
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Basic Information

Sensitivity
0.0075 ng/mL
Detection Range
0.015-3 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
40.8 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
solute carrier family 30 (zinc transporter), member 8
Function
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells.
Biological Process
Biological Process cellular zinc ion homeostasisISS:BHF-UCL
Biological Process insulin processingTAS:Reactome
Biological Process insulin secretionManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process positive regulation of insulin secretionISS:BHF-UCL
Biological Process regulation of sequestering of zinc ionISS:BHF-UCL
Biological Process regulation of vesicle-mediated transportISS:BHF-UCL
Biological Process response to glucoseManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process response to interferon-gammaIEA:Ensembl
Biological Process response to interleukin-1IEA:Ensembl
Biological Process response to zinc ionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process sequestering of zinc ionManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process zinc ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process zinc ion transportManual Assertion Based On ExperimentIDA:BHF-UCL
Cellular Location
Cell membrane
Cytoplasmic vesicle, secretory vesicle membrane
Associated with insulin and glucagon secretory granules.
Topology
Cytoplasmic: 1-79
Helical: 80-100
Extracellular: 101-103
Helical: 104-124
Cytoplasmic: 125-140
Helical: 141-161
Extracellular: 162-175
Helical: 176-196
Cytoplasmic: 197-217
Helical: 218-238
Extracellular: 239-245
Helical: 246-266
Cytoplasmic: 267-369
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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