Human TEAD1 ELISA Kit (V2LY-0626-LY5348)

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Tested Data
Datasheet
SDS
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Basic Information

Sensitivity
0.0097 ng/mL
Detection Range
0.02-4.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
47.9 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
TEAD1 Gene(Protein Coding) TEA Domain Transcription Factor 1
Function
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.
Biological Process
Biological Process embryonic organ developmentIBA:GO_Central1 Publication
Biological Process hippo signalingIDA:UniProtKB2 Publications
Biological Process positive regulation of cell growthIDA:ComplexPortal1 Publication
Biological Process positive regulation of DNA-templated transcriptionIMP:CAFA1 Publication
Biological Process positive regulation of miRNA transcriptionIMP:BHF-UCL1 Publication
Biological Process positive regulation of transcription by RNA polymerase IIIDA:ComplexPortal1 Publication
Biological Process protein-containing complex assemblyIMP:CAFA1 Publication
Biological Process regulation of transcription by RNA polymerase IIIBA:GO_Central1 Publication
Cellular Location
Nucleus
Involvement in disease
Sveinsson chorioretinal atrophy (SCRA):
Characterized by symmetrical lesions radiating from the optic disk involving the retina and the choroid.
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Rabbit Anti-TEAD1 Recombinant Antibody (CBYJT-2476) (CAT#: CBMAB-T1624-YJ)

Mouse Anti-TEAD1 Recombinant Antibody (CBYJT-2469) (CAT#: CBMAB-T1617-YJ)

Mouse Anti-TEAD1 Recombinant Antibody (CBYJT-2474) (CAT#: CBMAB-T1622-YJ)

Mouse Anti-TEAD1 Recombinant Antibody (CBYJT-2475) (CAT#: CBMAB-T1623-YJ)

Isotype control

For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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