Human THBS4 ELISA Kit (V2LY-0626-LY2922)

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Basic Information

Sensitivity
0.28 ng/mL
Detection Range
0.5-100 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
105.9 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Thrombospondin 4
Function
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner (By similarity).
Biological Process
Biological Process behavioral response to painSource:UniProtKB
Biological Process endothelial cell-cell adhesionSource:UniProtKB1 Publication
Biological Process myoblast migrationSource:UniProtKB1 Publication
Biological Process negative regulation of angiogenesisSource:UniProtKB1 Publication
Biological Process positive regulation of cell divisionSource:UniProtKB-KW
Biological Process positive regulation of endothelial cell proliferationSource:UniProtKB1 Publication
Biological Process positive regulation of neutrophil chemotaxisSource:UniProtKB1 Publication
Biological Process positive regulation of peptidyl-tyrosine phosphorylationSource:UniProtKB1 Publication
Biological Process regulation of tissue remodelingSource:UniProtKB
Biological Process response to endoplasmic reticulum stressSource:UniProtKB
Biological Process response to unfolded proteinSource:UniProtKB-KW
Biological Process tissue remodelingSource:UniProtKB-KW
Cellular Location
Endoplasmic reticulum
Sarcoplasmic reticulum
Secreted
Secreted, extracellular space
Secreted, extracellular space, extracellular matrix
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rat Thbs4 ELISA Kit (CAT#: V2LY-0626-LY2718)

Related Products

Rat Anti-Thbs4 Recombinant Antibody (CBYJT-2950) (CAT#: CBMAB-T2191-YJ)

Rat Thbs4 ELISA Kit (CAT#: V2LY-0626-LY2718)

Mouse Anti-THBS4 Recombinant Antibody (CBYJT-2949) (CAT#: CBMAB-T2190-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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