Rat Avpr1a ELISA Kit (V2LY-0626-LY1688)

Name: Rat Avpr1a ELISA Kit
SKU: V2LY-0626-LY1688
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.026 ng/mL

Detection Range

0.05-30 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Rat

Assay Type

Sandwich

Reactivity

Rat

Assay Time

1.5 h

Molecule Mass

47.7 kDa

Components

Pre-coated ELISA plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

arginine vasopressin receptor 1A

Function

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.

Biological Process

Activation of phospholipase C activity Source: ProtInc
Blood circulation Source: ProtInc
Calcium-mediated signaling Source: Ensembl
Cellular response to water deprivation Source: Ensembl
Generation of precursor metabolites and energy Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Grooming behavior Source: Ensembl
Maternal aggressive behavior Source: Ensembl
Maternal behavior Source: Ensembl
Myotube differentiation Source: Ensembl
Negative regulation of female receptivity Source: Ensembl
Negative regulation of transmission of nerve impulse Source: Ensembl
Penile erection Source: Ensembl
Positive regulation of cell growth Source: Ensembl
Positive regulation of cell population proliferation Source: ARUK-UCL
Positive regulation of cellular pH reduction Source: Ensembl
Positive regulation of cytosolic calcium ion concentration Source: ProtInc
Positive regulation of glutamate secretion Source: Ensembl
Positive regulation of heart rate Source: Ensembl
Positive regulation of prostaglandin biosynthetic process Source: Ensembl
Positive regulation of renal sodium excretion Source: Ensembl
Positive regulation of systemic arterial blood pressure Source: Ensembl
Positive regulation of vasoconstriction Source: GO_Central
Regulation of systemic arterial blood pressure by vasopressin Source: GO_Central
Response to corticosterone Source: Ensembl
Social behavior Source: Ensembl
Sperm ejaculation Source: Ensembl
Telencephalon development Source: Ensembl
Transport across blood-brain barrier Source: ARUK-UCL

Cellular Location

Cell membrane

Topology

Extracellular: 1-52 aa
Helical: 53-76 aa
Cytoplasmic: 77-88 aa
Helical: 89-110 aa
Extracellular: 111-125 aa
Helical: 126-147 aa
Cytoplasmic: 148-168 aa
Helical: 169-190 aa
Extracellular: 191-218 aa
Helical: 219-239 aa
Cytoplasmic: 240-293 aa
Helical: 294-313 aa
Extracellular: 314-331 aa
Helical: 332-351 aa
Cytoplasmic: 352-418 aa

Vollebregt, O., Koyama, E., Zai, C. C., Shaikh, S. A., Lisoway, A. J., Kennedy, J. L., & Beitchman, J. H. (2021). Evidence for association of vasopressin receptor 1A promoter region repeat with childhood onset aggression. Journal of Psychiatric Research, 140, 522-528.

Weiss, A., Wilson, V. A., & Hopkins, W. D. (2021). Early social rearing, the V1A arginine vasopressin receptor genotype, and autistic traits in chimpanzees. Autism Research.

Ripoll, G. V., Pifano, M., Garona, J., & Alonso, D. F. (2020). Commentary: Arginine vasopressin receptor 1a is a therapeutic target for castration-resistant prostate cancer. Frontiers in oncology, 9, 1490.

Nishina, K., Takagishi, H., Takahashi, H., Sakagami, M., & Inoue-Murayama, M. (2019). Association of polymorphism of arginine-vasopressin receptor 1A (AVPR1a) gene with trust and reciprocity. Frontiers in human neuroscience, 13, 230.

Zhao, N., Peacock, S. O., Lo, C. H., Heidman, L. M., Rice, M. A., Fahrenholtz, C. D., ... & Burnstein, K. L. (2019). Arginine vasopressin receptor 1a is a therapeutic target for castration-resistant prostate cancer. Science translational medicine, 11(498).

Landefeld, C. C., Hodgkinson, C. A., Spagnolo, P. A., Marietta, C. A., Shen, P. H., Sun, H., ... & Goldman, D. (2018). Effects on gene expression and behavior of untagged short tandem repeats: the case of arginine vasopressin receptor 1a (AVPR1a) and externalizing behaviors. Translational psychiatry, 8(1), 1-10.

Albee, L. J., LaPorte, H. M., Gao, X., Eby, J. M., Cheng, Y. H., Nevins, A. M., ... & Majetschak, M. (2018). Identification and functional characterization of arginine vasopressin receptor 1A: atypical chemokine receptor 3 heteromers in vascular smooth muscle. Open biology, 8(1), 170207.

Zhao, N., Peacock, S., Lo, C. H., Heidman, L., Magani, F., Rice, M., ... & Burnstein, K. (2018). Abstract A063: Preclinical evaluation of an arginine vasopressin receptor 1A (AVPR1A) antagonist in castration-resistant prostate cancer.

Wilson, V. A., Weiss, A., Humle, T., Morimura, N., Udono, T., Idani, G. I., ... & Inoue-Murayama, M. (2017). Chimpanzee personality and the arginine vasopressin receptor 1A genotype. Behavior Genetics, 47(2), 215-226.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

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