Human TNN ELISA Kit (V2LY-0626-LY3854)

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Tested Data
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Basic Information

Sensitivity
0.027 ng/mL
Detection Range
0.05-20 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
144.0 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Tenascin N
Function
Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (By similarity) (PubMed:17909022).
Involved in neurite outgrowth and cell migration in hippocampal explants (By similarity).
During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling (By similarity).
In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327).
Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells (PubMed:17909022).
Biological Process
Biological Process axonogenesis Source:Ensembl
Biological Process cell-matrix adhesion Source:GO_Central1 Publication
Biological Process dendrite self-avoidance Source:UniProtKB1 Publication
Biological Process negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation Source:UniProtKB
Biological Process negative regulation of neuron migration Source:UniProtKB1 Publication
Biological Process negative regulation of osteoblast differentiation Source:UniProtKB
Biological Process negative regulation of osteoblast proliferation Source:UniProtKB
Biological Process neuron projection extension Source:GO_Central1 Publication
Biological Process osteoblast development Source:UniProtKB
Biological Process positive regulation of neuron projection development Source:Ensembl
Biological Process positive regulation of sprouting angiogenesis Source:ComplexPortal1 Publication
Biological Process regulation of bone development Source:Ensembl
Biological Process regulation of cell adhesion Source:ComplexPortal1 Publication
Biological Process regulation of cell migration Source:ComplexPortal1 Publication
Biological Process regulation of smooth muscle tissue development Source:Ensembl
Cellular Location
Secreted, extracellular space, extracellular matrix
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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