Human TOLLIP ELISA Kit (V2LY-0626-LY5334)
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Basic Information
- Pre-coated ELISA plate: 12 wells * 8 detachable strips
- Standard solution: 0.5ml x1
- Standard diluent: 3ml x1
- Streptavidin-HRP: 6ml x1
- Stop solution: 6ml x1
- Substrate solution A: 6ml x1
- Substrate solution B: 6ml x1
- Wash buffer concentrate (25x): 20ml x1
- Biotinylated antibody: 1ml x1
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex (PubMed:10854325).
Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856).
Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates (PubMed:25042851).
The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
In a complex with TOM1, recruits ubiquitin-conjugated proteins onto early endosomes (PubMed:15047686).
Binds to phosphatidylinositol 3-phosphate (PtdIns3P) (PubMed:26320582).
Biological Process epithelial cell differentiation Source:UniProtKB1 Publication
Biological Process inflammatory response Source:UniProtKB-KW
Biological Process innate immune response Source:UniProtKB-KW
Biological Process interleukin-1-mediated signaling pathway Source:Ensembl
Biological Process leukocyte activation Source:UniProtKB1 Publication
Biological Process phosphorylation Source:UniProtKB1 Publication
Biological Process positive regulation of protein sumoylation Source:Ensembl
Biological Process protein localization to endosome Source:UniProtKB1 Publication
Biological Process signal transduction Source:UniProtKB1 Publication
Biological Process ubiquitin-dependent protein catabolic process Source:GO_Central1 Publication
Endosome
Early endosome
Localized to endo/exosomal vesicles.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Rat Tollip ELISA Kit (CAT#: V2LY-0626-LY1566)
Antibody Pairs
TOLLIP Matched Antibody Pair (1251) (CAT#: APMAB-1251LY)
Related Products
Mouse Anti-TOLLIP Recombinant Antibody (CBYJT-4149) (CAT#: CBMAB-T3598-YJ)
Rat Anti-Tollip Recombinant Antibody (Kimmy-1) (CAT#: CBMAB-T3609-YJ)
Mouse Anti-TOLLIP Recombinant Antibody (CBYJT-4150) (CAT#: CBMAB-T3599-YJ)
Mouse Anti-TOLLIP Recombinant Antibody (CBYJT-4155) (CAT#: CBMAB-T3606-YJ)
Mouse Anti-TOLLIP Recombinant Antibody (CBYJT-4156) (CAT#: CBMAB-T3607-YJ)
TOLLIP Matched Antibody Pair (1251) (CAT#: APMAB-1251LY)
Rat Tollip ELISA Kit (CAT#: V2LY-0626-LY1566)
Mouse Anti-TOLLIP Recombinant Antibody (CBYJT-4154) (CAT#: CBMAB-T3604-YJ)
Mouse Anti-Tollip Recombinant Antibody (Kimmy-2) (CAT#: CBMAB-T3610-YJ)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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