Human TRPV2 ELISA Kit (V2LY-0626-LY2952)

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Tested Data
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Basic Information

Sensitivity
0.008 ng/mL
Detection Range
0.015-3 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
86.0 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
TRPV2 Gene(Protein Coding)


Transient Receptor Potential Cation Channel Subfamily V Member 2
Function
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
Biological Process
Biological Process calcium ion import across plasma membrane Source:GO_Central1 Publication
Biological Process calcium ion transmembrane transport Source:Reactome
Biological Process positive regulation of axon extension Source:Ensembl
Biological Process positive regulation of calcium ion import Source:Ensembl
Biological Process positive regulation of cold-induced thermogenesis Source:YuBioLabBy Similarity
Biological Process response to heat Source:InterPro
Biological Process response to temperature stimulus Source:MGI1 Publication
Biological Process sensory perception Source:ProtInc1 Publication
Cellular Location
Cell membrane
Cytoplasm
Melanosome
Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity).
Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Topology
Cytoplasmic: 1-390
Helical: 391-411
Extracellular: 412-434
Helical: 435-455
Cytoplasmic: 456-471
Helical: 472-492
Extracellular: 493
Helical: 494-514
Cytoplasmic: 515-537
Helical: 538-558
Pore-forming: 572-609
Helical: 622-642
Cytoplasmic: 643-764
PTM
N-glycosylated.
Phosphorylated by PKA.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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