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IFIT3 Matched Antibody Pair (591) (APMAB-591LY)

This antibody pair set can be used for detecting and quantifying protein level of human IFIT3.
See all IFIT3 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-IFIT3 polyclonal antibody, 100 ug
Detection Antibody
Anti-IFIT3 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
IFIT3 (Interferon Induced Protein With Tetratricopeptide Repeats 3) is a Protein Coding gene. Diseases associated with IFIT3 include Systemic Lupus Erythematosus. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. Gene Ontology (GO) annotations related to this gene include identical protein binding. An important paralog of this gene is IFIT2.
Alternative Names
Interferon Induced Protein With Tetratricopeptide Repeats 3
Entrez Gene ID
UniProt ID

Zhang, W., Li, Y., Xin, S., Yang, L., Jiang, M., Xin, Y., ... & Lu, J. (2023). The emerging roles of IFIT3 in antiviral innate immunity and cellular biology. Journal of Medical Virology, 95(1), e28259.

Schindewolf, C., Lokugamage, K., Vu, M. N., Johnson, B. A., Scharton, D., Plante, J. A., ... & Menachery, V. D. (2023). SARS-CoV-2 uses nonstructural protein 16 to evade restriction by IFIT1 and IFIT3. Journal of virology, 97(2), e01532-22.

Wu, Y., Song, X., Cui, D., & Zhang, T. (2022). IFIT3 and IFIT5 play potential roles in innate immune response of porcine pulmonary microvascular endothelial cells to highly pathogenic porcine reproductive and respiratory syndrome virus. Viruses, 14(9), 1919.

Chai, B., Tian, D., Zhou, M., Tian, B., Yuan, Y., Sui, B., ... & Zhao, L. (2021). Murine Ifit3 restricts the replication of Rabies virus both in vitro and in vivo. Journal of General Virology, 102(7), 001619.

Chikhalya, A., Dittmann, M., Zheng, Y., Sohn, S. Y., Rice, C. M., & Hearing, P. (2021). Human IFIT3 protein induces interferon signaling and inhibits adenovirus immediate early gene expression. Mbio, 12(6), e02829-21.

Wang, Z., Qin, J., Zhao, J., Li, J., Li, D., Popp, M., ... & Bruns, C. J. (2020). Inflammatory IFIT3 renders chemotherapy resistance by regulating post-translational modification of VDAC2 in pancreatic cancer. Theranostics, 10(16), 7178.

Xu, F., Song, H., An, B., Xiao, Q., Cheng, G., & Tan, G. (2019). NF-κB-dependent IFIT3 induction by HBx promotes hepatitis B virus replication. Frontiers in microbiology, 10, 2382.

Pidugu, V. K., Wu, M. M., Yen, A. H., Pidugu, H. B., Chang, K. W., Liu, C. J., & Lee, T. C. (2019). IFIT1 and IFIT3 promote oral squamous cell carcinoma metastasis and contribute to the anti-tumor effect of gefitinib via enhancing p-EGFR recycling. Oncogene, 38(17), 3232-3247.

Fleith, R. C., Mears, H. V., Leong, X. Y., Sanford, T. J., Emmott, E., Graham, S. C., ... & Sweeney, T. R. (2018). IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA. Nucleic acids research, 46(10), 5269-5285.

Johnson, B., VanBlargan, L. A., Xu, W., White, J. P., Shan, C., Shi, P. Y., ... & Amarasinghe, G. K. (2018). Human IFIT3 modulates IFIT1 RNA binding specificity and protein stability. Immunity, 48(3), 487-499.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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