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KHSRP Matched Antibody Pair (661) (APMAB-661LY)

This antibody pair set can be used for detecting and quantifying protein level of human KHSRP.
See all KHSRP antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-KHSRP monoclonal, IgG2b antibody, 100 ug
Detection Antibody
Anti-KHSRP Biotinylated mouse monoclonal, IgG2a antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]; Gherzi et al., 2004 [PubMed 15175153]).[supplied by OMIM, Apr 2010]
Alternative Names
KH-Type Splicing Regulatory Protein; FUSE-Binding Protein 2; FUBP2; KSRP; P75; Far Upstream Element-Binding Protein 2; KH Type-Splicing Regulatory Protein; FUSE Binding Protein 2; FBP2;
Entrez Gene ID
8570
UniProt ID
Q92945

Du, Y., Zhang, J. Y., Gong, L. P., Feng, Z. Y., Wang, D., Pan, Y. H., ... & Shao, C. K. (2022). Hypoxia-induced ebv-circLMP2A promotes angiogenesis in EBV-associated gastric carcinoma through the KHSRP/VHL/HIF1α/VEGFA pathway. Cancer letters, 526, 259-272.

Olguin, S. L., Patel, P., Buchanan, C. N., Dell’Orco, M., Gardiner, A. S., Cole, R., ... & Perrone-Bizzozero, N. I. (2022). KHSRP loss increases neuronal growth and synaptic transmission and alters memory consolidation through RNA stabilization. Communications Biology, 5(1), 672.

Singh, S., Shaikh, I. A., More, S. S., Mahnashi, M. H., Almohaimeed, H. M., El-Sherbiny, M., ... & Iqubal, S. S. (2022). Blockage of KHSRP-NLRP3 by MCC950 can reverse the effect of manganese-induced neuroinflammation in N2a cells and rat brain. International Journal of Molecular Sciences, 23(21), 13224.

Xu, J., Wang, D., Ma, H., Zhai, X., Huo, Y., Ren, Y., ... & Yu, J. (2022). KHSRP combines transcriptional and posttranscriptional mechanisms to regulate monocytic differentiation. Blood Science, 4(03), 103-115.

Huang, X., Liu, X., Du, B., Liu, X., Xue, M., Yan, Q., ... & Wang, Q. (2021). LncRNA LINC01305 promotes cervical cancer progression through KHSRP and exosome-mediated transfer. Aging (Albany NY), 13(15), 19230.

Yao, X. Y., Liu, J. F., Luo, Y., Xu, X. Z., & Bu, J. (2021). LncRNA HOTTIP facilitates cell proliferation, invasion, and migration in osteosarcoma by interaction with PTBP1 to promote KHSRP level. Cell Cycle, 20(3), 283-297.

Pan, R., Cai, W., Sun, J., Yu, C., Li, P., & Zheng, M. (2020). Inhibition of KHSRP sensitizes colorectal cancer to 5‐fluoruracil through miR‐501‐5p‐mediated ERRFI1 mRNA degradation. Journal of Cellular Physiology, 235(2), 1576-1587.

Taniuchi, K., & Ogasawara, M. (2020). KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer. Oncotarget, 11(2), 131.

Yan, M., Sun, L., Li, J., Yu, H., Lin, H., Yu, T., ... & Yao, M. (2019). RNA-binding protein KHSRP promotes tumor growth and metastasis in non-small cell lung cancer. Journal of experimental & clinical cancer research, 38, 1-17.

Gou, Q., Gao, L., Nie, X., Pu, W., Zhu, J., Wang, Y., ... & Peng, Y. (2018). Long noncoding RNA AB074169 inhibits cell proliferation via modulation of KHSRP-mediated CDKN1a expression in papillary thyroid carcinoma. Cancer research, 78(15), 4163-4174.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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