Mouse Anti-GPX2 Recombinant Antibody (CAP851) (V2LY-0226-LY977)

Go to compare Compare Online Inquiry
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CAP851
Application
WB
Immunogen
Recombinant human Glutathione Peroxidase 2 (Gly41-Ile190).
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, trehalose
Preservative
None
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
glutathione peroxidase 2
Entrez Gene ID
Human2877
Mouse14776
Rat29326
UniProt ID
HumanP18283
MouseQ9JHC0
RatP83645
Function
Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors.
Biological Process
Response to oxidative stress Source: InterPro
Cellular Location
Cytoplasm. Mainly cytoplasmic.

Xu, H., Hu, C., Wang, Y., Shi, Y., Yuan, L., Xu, J., ... & Cheng, X. (2023). Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism. Oncogene, 1-13.

Cui, Z., Xu, L., Wu, H., Wang, M., Lu, L., & Wu, S. (2023). Glutathione peroxidase 2: A key factor in the development of microsatellite instability in colon cancer. Pathology-Research and Practice, 243, 154372.

Ren, Z., Liang, H., Galbo Jr, P. M., Dharmaratne, M., Kulkarni, A. S., Fard, A. T., ... & Hazan, R. B. (2022). Redox signaling by glutathione peroxidase 2 links vascular modulation to metabolic plasticity of breast cancer. Proceedings of the National Academy of Sciences, 119(8), e2107266119.

Wang, M., Chen, X., Fu, G., & Ge, M. (2022). Glutathione peroxidase 2 overexpression promotes malignant progression and cisplatin resistance of KRAS‑mutated lung cancer cells. Oncology Reports, 48(6), 1-14.

Ahmed, K. M., Veeramachaneni, R., Deng, D., Putluri, N., Putluri, V., Cardenas, M. F., ... & Frederick, M. J. (2022). Glutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response. Journal for immunotherapy of cancer, 10(8), e004752.

Canizal-García, M., Olmos-Orizaba, B. E., Moreno-Jiménez, M., Calderón-Cortés, E., Saavedra-Molina, A., & Cortés-Rojo, C. (2021). Glutathione peroxidase 2 (Gpx2) preserves mitochondrial function and decreases ROS levels in chronologically aged yeast. Free Radical Research, 55(2), 165-175.

Guo, B., Liao, W., & Wang, S. (2021). The clinical significance of glutathione peroxidase 2 in glioblastoma multiforme. Translational neuroscience, 12(1), 032-039.

Du, H., Chen, B., Jiao, N. L., Liu, Y. H., Sun, S. Y., & Zhang, Y. W. (2020). Elevated glutathione peroxidase 2 expression promotes cisplatin resistance in lung adenocarcinoma. Oxidative Medicine and Cellular Longevity, 2020.

Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Mouse Anti-GPX2 Recombinant Antibody (CAP851)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.