Mouse Anti-GRK3 Recombinant Antibody (CAP223) (V2LY-0226-LY1323)

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CAP223
Application
WB
Immunogen
E. coli-derived recombinant human GRK3 (Pro469-Leu688).
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, trehalose
Preservative
None
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
G protein-coupled receptor kinase 3
Entrez Gene ID
Human156
Mouse110355
Rat25238
UniProt ID
HumanP25098
MouseQ99MK8
RatP26817
Function
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
Biological Process
Desensitization of G protein-coupled receptor signaling pathway Source: GO_Central
G protein-coupled receptor signaling pathway Source: GO_Central
Protein phosphorylation Source: GO_Central
Receptor internalization Source: UniProtKB
Regulation of signal transduction Source: GO_Central
Signal transduction Source: ProtInc
Cellular Location
Cytosol; Plasma membrane
PTM
Ubiquitinated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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