Mouse Edil3 ELISA Kit (V2LY-0626-LY5832)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.019 ng/mL
Detection Range
0.037-2.4 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
53.7 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
EGF-like repeats and discoidin I-like domains 3
Research Area
Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.
Biological Process
Cell adhesion Source: UniProtKB-KW
Positive regulation of cell-substrate adhesion Source: Ensembl
Cellular Location
Secreted

Niu, X., Han, Q., Li, X., Li, J., Liu, Y., Li, Y., ... & Zhang, K. (2022). EDIL3 influenced the αvβ3‐FAK/MEK/ERK axis of endothelial cells in psoriasis. Journal of Cellular and Molecular Medicine.

Niu, X., Han, Q., Li, X., Li, J., Liu, Y., Li, Y., ... & Zhang, K. (2022). EDIL3 influenced the αvβ3‐FAK/MEK/ERK axis of endothelial cells in psoriasis. Journal of Cellular and Molecular Medicine.

Sagkan, R. I., & Akin, D. F. B. (2021). Epidermal Growth Factor-Like Repeats and Discoidin I-Like Domains 3 is a Novel Regulator of Epithelial-Mesenchymal Transition in Clear Cell Renal Cell Carcinoma: In Silico Analysis. Erciyes Medical Journal, 43(2), 122-130.

AKIN, D. F., & ILIKCI, R. (2021). Mutations and expression profile of EDIL3 and correlation with HIF1A and tumor-associated carbonic anhydrases in pancreatic cancer. Clinical and Experimental Health Sciences, 11(3), 418-425.

Niu, X., Han, Q., Liu, Y., Li, J., Hou, R., Li, J., & Zhang, K. (2020). Psoriasis-associated angiogenesis is mediated by EDIL3. Microvascular Research, 132, 104056.

Gasca, J., Flores, M. L., Jiménez-Guerrero, R., Sáez, M. E., Barragán, I., Ruíz-Borrego, M., ... & Japón, M. A. (2020). EDIL3 promotes epithelial–mesenchymal transition and paclitaxel resistance through its interaction with integrin αVβ3 in cancer cells. Cell death discovery, 6(1), 1-14.

Kun, Z., Xin, G., Tao, W., Chenglong, Z., Dongsheng, W., Liang, T., ... & Jianru, X. (2019). Tumor derived EDIL3 modulates the expansion and osteoclastogenesis of myeloid derived suppressor cells in murine breast cancer model. Journal of bone oncology, 16, 100238.

Wei, X., Zhang, C., Xie, Z., Teng, X., Wang, Z., Zheng, H., ... & Li, J. (2019). EGF-like repeats and discoidin I-like domain 3 (EDIL3) deficiency improves post-myocardial infarction healing via neutrophil extracellular traps (NETs) mediated pro-inflammatory macrophage polarization.

Stapane, L., Le Roy, N., Hincke, M. T., & Gautron, J. (2019). The glycoproteins EDIL3 and MFGE8 regulate vesicle-mediated eggshell calcification in a new model for avian biomineralization. Journal of Biological Chemistry, 294(40), 14526-14545.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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